Suipoxvirus
Suipoxvirus | |
---|---|
Virus classification | |
(unranked): | Virus |
Realm: | Varidnaviria |
Kingdom: | Bamfordvirae |
Phylum: | Nucleocytoviricota |
Class: | Pokkesviricetes |
Order: | Chitovirales |
Family: | Poxviridae |
Subfamily: | Chordopoxvirinae |
Genus: | Suipoxvirus |
Suipoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae. Swine serve as natural hosts. There is only one species in this genus: Swinepox virus. Diseases associated with this genus include asymptomatic skin disease.[1][2]
Structure
Viruses in Suipoxvirus are enveloped, with brick-shaped geometries. Genomes are linear, around 175 kilobases in length.[1]
Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|
Suipoxvirus | Brick-shaped | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host glycosaminoglycans (GAGs), which mediates endocytosis of the virus into the host cell. The virion undergoes fusion with the plasma membrane to release the core into the host cytoplasm. Early genes are transcribed in the cytoplasm by viral RNA polymerase. Early expression begins at 30 minutes post-infection. The core is completely uncoated as early expression ends, and the viral genome is now free in the cytoplasm.[citation needed]
Intermediate genes are expressed, triggering genomic DNA replication at approximately 100 minutes post-infection. Late genes are expressed from 140 min to 48 hours post-infection, producing all structural proteins. The assembly of progeny virions starts in cytoplasmic viral factories and produces a spherical, immature particle. This virus particle matures into a brick-shaped, intracellular mature virion (IMV). This IMV virion can be released upon cell lysis, or can acquire a second double membrane from trans-Golgi and bud as external enveloped virion (EEV).[citation needed]
Replication follows the DNA strand displacement model. DNA-templated transcription is the method of transcription. The virus exits the host cell by existing in occlusion bodies after cell death and remaining infectious until finding another host. Swine serve as the natural host.[1]
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Suipoxvirus | Swine | None | Glycosaminoglycans | Lysis; budding | Cytoplasm | Cytoplasm | Unknown |
Swinepox
Swinepox is a worldwide disease of the pig, caused by a virus of the family
References
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 22 May 2021.
- ISBN 978-0-12-253056-2.
- ^ Carter, G.R.; Wise, D.J. (2006). "Poxviridae". A Concise Review of Veterinary Virology. Retrieved 13 June 2006.
External links