Transient neonatal diabetes
| Transient neonatal diabetes | |
|---|---|
 | |
| Transient neonatal diabetes mellitus is inherited in an autosomal dominant manner[1] | |
| Specialty | Pediatrics  |
Transient neonatal diabetes mellitus (TNDM) is a form of
maturity onset diabetes of the young
(MODY).
Types
| Type | OMIM
|
Gene | Locus | Description |
|---|---|---|---|---|
| TNDM1 | 601410 | ZFP57, PLAGL1 | 6p22.1, 6q24.2 | |
| TNDM2 | 610374 | ABCC8 | 11p15.1 | Due to the mutations of the other subunit of the KATP channel, SUR1, which is encoded by the ABCC8 gene.[2] |
| TNDM3 | 610582 | KCNJ11
|
11p15.1 |
Cause
This condition has to do with genetics and is often associated with having an added Chromosome 7 gene (mostly from the paternal side).[citation needed]
The form on chromosome 6 can involve imprinting.[3][4]
Diagnosis
![[icon]](/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (September 2017) |
Management
| This section is empty. You can help by adding to it. (September 2017) |
See also
- Permanent neonatal diabetes mellitus
References
- ^ "OMIM Entry - # 610582 - DIABETES MELLITUS, TRANSIENT NEONATAL, 3". omim.org. Retrieved 12 September 2017.
- PMID 18497752.
- ISBN 978-3-8055-8385-5. Retrieved 10 November 2010.
- ^ "Other Forms (MODY, LADA, Neonatal)". www.DiabetesCare.net. DiabetesCare.net. Retrieved 20 November 2014.