Triamcinolone hexacetonide

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Triamcinolone hexacetonide
Clinical data
Trade namesAristospan
Other namesTriamcinolone acetonide 21-tebutate; Triamcinolone acetonide 21-(tert-butylacetate); 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-(3,3-dimethylbutyrate); 9α-Fluoro-11β-hydroxy-16α,17α-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione 21-(3,3-dimethylbutyrate)
Drug classCorticosteroid; Glucocorticoid
Legal status
Legal status
Identifiers
  • 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl 3,3-dimethylbutanoate
JSmol)
  • C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)COC(=O)CC(C)(C)C)CCC5=CC(=O)C=C[C@@]53C)F)O
  • InChI=1S/C30H41FO7/c1-25(2,3)15-24(35)36-16-22(34)30-23(37-26(4,5)38-30)13-20-19-9-8-17-12-18(32)10-11-27(17,6)29(19,31)21(33)14-28(20,30)7/h10-12,19-21,23,33H,8-9,13-16H2,1-7H3/t19-,20-,21-,23+,27-,28-,29-,30+/m0/s1
  • Key:TZIZWYVVGLXXFV-FLRHRWPCSA-N

Triamcinolone hexacetonide (brand name Aristospan; also known as triamcinolone acetonide 21-tebutate) is a

synthetic glucocorticoid corticosteroid.[3][4][5]

It is on the World Health Organization's List of Essential Medicines.[6]

References

  1. ^ "Arthritis". Health Canada. 8 May 2018. Retrieved 13 April 2024.
  2. ^ "Regulatory Decision Summary for Triamcinolone Hexacetonide Injectable Suspension". Drug and Health Products Portal. 12 December 2017. Retrieved 13 April 2024.
  3. ISBN 978-1-4757-2085-3
    .
  4. ISBN 978-3-88763-075-1
    .
  5. ISBN 978-94-011-4439-1
    .
  6. hdl:10665/371090
    . WHO/MHP/HPS/EML/2023.02.
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