7α-Hydroxyepiandrosterone

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7α-Hydroxyepiandrosterone
Names
IUPAC name
3β,7α-Dihydroxy-5α-androstan-17-one
Systematic IUPAC name
(3aS,3bR,4R,5aR,7S,9aS,9bS,11aS)-4,7-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-one
Other names
7α-OH-EPIA; 5α-Androstan-3β,7α-diol-17-one
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
UNII
  • InChI=1S/C19H30O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h11-15,17,20-21H,3-10H2,1-2H3/t11-,12+,13+,14+,15-,17+,18+,19+/m1/s1
    Key: VFPMCLQMAUVEHD-KMQZSKAMSA-N
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)[C@H](O)C[C@H]1C[C@@H](O)CC[C@]31C
Properties
C19H30O3
Molar mass 306.446 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

7α-Hydroxyepiandrosterone (7α-OH-EPIA), also known as 3β,7α-dihydroxy-5α-androstan-17-one, is an

endogenous, naturally occurring metabolite of epiandrosterone and dehydroepiandrosterone (DHEA) that is formed by the enzyme CYP7B1 in tissues such as the liver and brain.[1][2][3]

See also

References

  1. ISBN 978-0-08-054423-6
    .
  2. ISBN 978-2-7430-1918-1
    .
  3. S2CID 54408683
    .



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