3α-Dihydroprogesterone

Source: Wikipedia, the free encyclopedia.
3α-Dihydroprogesterone
Names
IUPAC name
3α-Hydroxypregn-4-en-20-one
Systematic IUPAC name
1-[(1S,3aS,3bS,7R,9aR,9bS,11aS)-7-Hydroxy-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]ethan-1-one
Other names
3α-Dihydroprogesterone
Identifiers
3D model (
JSmol
)
ChemSpider
UNII
  • InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,15-19,23H,4-11H2,1-3H3/t15-,16+,17-,18+,19+,20+,21-/m1/s1
    Key: QWVWXRKHAXWWSV-QYYVTAPASA-N
SMILES
  • CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C[C@@H](CC[C@]34C)O)C
Properties
C21H32O2
Molar mass 316.485 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

3α-Dihydroprogesterone (3α-DHP), also known as 3α-hydroxyprogesterone, as well as pregn-4-en-3α-ol-20-one, is an

5α-reductase inhibitors like finasteride.[1] No data were available on the progestogenic activity of 3α-DHP as of 1977.[3] Levels of 5α-DHP have been quantified.[4]

Chemistry

See also: List of neurosteroids

See also

References

  1. ^
    ISBN 978-0-08-054423-6
    .
  2. Wikidata Q48124086
    .
  3. S2CID 28420255
    .
  4. PMID 26353176
    .
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