Annular elastolytic giant-cell granuloma
| Annular elastolytic giant-cell granuloma | |
|---|---|
| Specialty | Dermatology  |
Annular elastolytic giant-cell granuloma (also known as "Giant cell elastophagocytosis,"[1] "Meischer's granuloma,"[2] "Miescher's granuloma of the face"[1]) is a cutaneous condition characterized histologically by a dermal infiltrate of macrophages.[1][2]: 706
Signs and symptoms
The most common presentation of annular elastolytic giant-cell granuloma is one or more annular or ring-shaped patches with elevated borders, atrophy, and central hypopigmentation. Generalized papular lesions may also be observed.[3][4] Although it sporadically affects covered areas as well, annular elastolytic giant-cell granuloma is generally thought to be a disease that primarily affects sun-exposed areas.[5][6]
Diagnosis
Treatment
The handling of these cases is debatable, with differing results from topical treatments using tacrolimus, retinoids, and corticosteroids, and systemic treatments using methotrexate, isotretinoin, clofazimine, acitretin, and hydroxychloroquine.[8]
See also
- Actinic granuloma
- List of cutaneous conditions
References
- ^ ISBN 978-1-4160-2999-1.
- ^ ISBN 978-0-7216-2921-6.
- S2CID 23145183.
- S2CID 19674767.
- PMID 3622881.
- S2CID 31861362.
- PMID 26904442.
- PMID 21220900.