Acrodermatitis chronica atrophicans
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| Acrodermatitis chronica atrophicans | |
|---|---|
| Other names | Herxheimer disease[1]: 1102 and Primary diffuse atrophy[2]: 293 |
| Specialty | Dermatology  |
| Causes | untreated infection with Borrelia afzelii |
Acrodermatitis chronica atrophicans (ACA) is a
ACA is a dermatological condition that takes a chronically progressive course and finally leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is often observed, specifically polyneuropathy.
This progressive skin process is due to the effect of continuing active infection with the
Presentation
The rash caused by ACA is most evident on the extremities. It begins with an
Cause
![[icon]](/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (March 2017) |
Diagnosis
Generally a two-step approach is followed. First, a screening test involving IgM and IgG ELISA. If the ELISA screening has a positive or equivocal result, then the second step is to perform a Western Blot as a confirmatory test.
Other methods include microscopy and culture (in modified Kelly's medium) of skin biopsy or blood samples.
Treatment
History
The first record of ACA was made in 1883 in
See also
- Erythema migrans
- List of cutaneous conditions
- Lyme disease
References
- ISBN 978-1-4160-2999-1.
- ISBN 978-0-7216-2921-6.
- ^ S2CID 218911807.
- PMID 35201695.
Bibliography
- Stanek G & Strle F (2008) Lyme Disease—European Perspective| Infectious Disease Clinics of North America | Volume 22 | Issue 2 | June 2008, Pages 327-339|Abstract
