Elephantiasis nostras

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Elephantiasis nostras
SpecialtyDermatology

Elephantiasis nostras is a disease that usually affects the lower legs or scrotum.[1] Swelling is accompanied by rough nodules or wart-like plaques on the skin. If the disease is not treated, it eventually results in pain and immobility.[2]

The disease can be described as a cutaneous condition, a final hypertrophic fibrosis following long standing

chronic lymphangitis.[3]
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Causes

Although elephantiasis nostras resembles the

elephantiasis caused by helminths, it is not a filarial disease. Instead, it is a complication of chronic lymphedema.[1] Both elephantiasis nostras and filarial elephantiasis are characterized by impaired lymphatic drainage, which results in excess fluid accumulation.[2]

Treatment

Treatment consists of antibiotics, elevation of the affected limb, and compression. For persons with elephantiasis nostras who are overweight or obese, weight loss is recommended.[2] Oral retinoids have been used to treat the cutaneous manifestations of the disease.[1]

See also

  • Chronic lymphangitis
  • Elephantiasis
  • Skin lesion
  • List of cutaneous conditions

References