Eosinophilic folliculitis

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Eosinophilic folliculitis
Other namesEosinophilic pustular folliculitis, Sterile eosinophilic pustulosis"[1]
SpecialtyDermatology

Eosinophilic folliculitis is an

papules) centered on hair follicles and typically found on the upper body, sparing the abdomen and legs. The name eosinophilic folliculitis refers to the predominant immune cells associated with the disease (eosinophils
) and the involvement of the hair follicles.

Pathophysiology

The cause of EF is unknown. A variety of

autoimmune process has also been investigated.[6]

Diagnosis

Eosinophilic folliculitis may be suspected clinically when an individual with HIV exhibits the classic symptoms. The diagnosis can be supported by the finding of eosinophilia but a skin biopsy is necessary to establish it. Skin biopsies reveal lymphocytic and eosinophilic inflammation around the hair follicles.

Treatment

Treatment of eosinophilic folliculitis in people with HIV typically begins with the initiation of

PUVA, topical tacrolimus, and isotretinoin.[7]

Epidemiology

Eosinophilic folliculitis associated with HIV infection typically affects individuals with advanced HIV and low T helper cell counts.[8] It affects both men and women as well as children with HIV and is found throughout the world.

EF may also affect individuals with hematologic disease such as leukemia and lymphoma.[9] It may also affect otherwise normal infants in a self-limited form.[10] HIV-negative individuals can also develop EF — this is more common in Japan.[11]

See also

References

  1. ISBN 0-7216-2921-0
    .
  2. PMID 4193219
    .
  3. S2CID 33746330
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  4. S2CID 1196523
    .
  5. PMID 7661619
    .
  6. S2CID 12727217
    .
  7. S2CID 72079927
    .
  8. S2CID 71615655
    .
  9. S2CID 45311563
    .
  10. S2CID 36497326
    .
  11. S2CID 26787648
    .

External links
Retrieved from "https://en.wikipedia.org/w/index.php?title=Eosinophilic_folliculitis&oldid=1165182588"