K_ir2.6

The K_ir2.6 also known as inward rectifier potassium channel 18 is a protein that in humans is encoded by the KCNJ18

Function

Inwardly rectifying potassium channels, such as K_ir2.6, maintain resting membrane potential in excitable cells and aid in repolarization of cells following depolarization. K_ir2.6 is primarily expressed in skeletal muscle and is transcriptionally regulated by

Mutations in this gene have been linked to thyrotoxic periodic paralysis.^[1]

References

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.