11β-Hydroxytestosterone

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11β-Hydroxytestosterone
Names
IUPAC name
11β,17β-Dihydroxyandrost-4-en-3-one
Systematic IUPAC name
(1S,3aS,3bS,9aR,9bS,11aS)-1,10-Dihydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard
 100.162.057 Edit this at Wikidata
EC Number
  • 634-040-0
KEGG
UNII
  • InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14-,15-,16-,17+,18-,19-/m0/s1
  • C1C2=CC(CC[C@@]2([C@]3([C@H](C[C@]4([C@]([C@@]3(C1)[H])(CC[C@@H]4O)[H])C)O)[H])C)=O
Properties
C19H28O3
Molar mass 304.430 g·mol−1
Hazards
GHS labelling:
GHS08: Health hazard
Danger
H351, H360
P201, P202, P281, P308+P313, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

11β-Hydroxytestosterone is an

endogenous steroid, a metabolite of testosterone.[1][2][3][4] Although it may not have significant androgenic activity, it may still be an important precursor to androgenic molecules.[4]

See also

References

  1. S2CID 209748543
    . CYP11B1 and 2 have also been shown to 11β-hydroxylate T, yielding 11β-hydroxytestosterone (11OHT), though the levels produced by the adrenal are low due to the limited availability of adrenal derived T
  2. PMID 33094617
    .
  3. S2CID 3700135
    .
  4. ^
    S2CID 257943362
    .


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