ADP—thymidine kinase
| ADP-thymidine kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In
enzymology, an ADP—thymidine kinase (EC 2.7.1.118) is an enzyme that catalyzes the chemical reaction
- ADP + thymidine AMP + thymidine 5'-phosphate
Thus, the two
substrates of this enzyme are ADP and thymidine, whereas its two products are AMP and thymidine 5'-phosphate
.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:thymidine 5'-phosphotransferase. Other names in common use include ADP:dThd phosphotransferase, and adenosine diphosphate-thymidine phosphotransferase.
References
- Falke D, Labenz J, Brauer D, Muller WE (1982). "Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase". Biochim. Biophys. Acta. 708 (1): 99–103. PMID 6293576.
