Antiprogestogen
Antiprogestogen | ||
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Chemical class Steroidal | | |
Legal status | ||
In Wikidata |
Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of
Antiprogestogens are used as
Several hundred antiprogestogens have been developed, but only three, mifepristone, lilopristone, and onapristone, have been given to humans, and of these, only mifepristone has been approved and introduced for clinical use.[5]
Progestins, including progesterone are important for the body to prepare the uterus for implantation of fertilized egg during the luteal phase of the menstrual cycle and, if fertilization, implantation, and other events necessary for pregnancy occur, increased progestin (i.e. progesterone) levels are heavily involved in maintaining the pregnancy. Blocking the effects of progestins, such as progesterone, is associated with anti-gestational events. [6]
See also
References
- ISBN 978-0-7817-4868-1.
- PMID 17086932.
- S2CID 23295715.
- ^ Le, Tao; Bhushan, Vikas; Qiu, Connie; Chalise, Anup; Kaparaliotis, Panagiotis (2023). First Aid. McGraw Hill.
- ISBN 978-0-203-01621-3.
- ^ Le, Tao; Bhushan, Vikas; Qiu, Connie; Chalise, Anup; Kaparaliotis, Panagiotis (2023). First Aid. McGraw Hill.
External links
- Media related to Antiprogestogens at Wikimedia Commons
- Antiprogestin entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates