Secondary amino acid
In
secondary amine (>NH). Secondary amino acids can be classified to cyclic acids, such as proline, and acyclic N-substituted amino acids.[1][2]
In nature, proline, hydroxyproline, pipecolic acid and sarcosine are well-known secondary amino acids. Proline is the only proteinogenic secondary amino acids. Other secondary amino acids are non-proteinogenic amino acids. In protein, hydroxyproline is incorporated into protein by hydroxylation of proline. Pipecolic acid, a heavier analog of proline, is found in efrapeptin. Sarcosine is a N-methylized glycine so its methyl group is used in many biochemical reactions. Azetidine-2-carboxylic acid, which is a smaller homolog of proline in plants.
Properties
Proline and its higher homolog pipecolic acid affect the
efrapeptin C.[1]
Ninhydrin tests of proline and hydroxyproline give yellow results.
In
enzymology, a N-methyl-L-amino-acid oxidase
is an oxidase of a subtype of secondary amino acids.
See also
- Imino acid
- Imidic acid
- Secondary amine
References
External links
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