Vascular organ of lamina terminalis

Source: Wikipedia, the free encyclopedia.
Vascular organ of lamina terminalis
Details
Identifiers
Latinorganum vasculosum laminae terminalis
MeSHD066278
NeuroNames383
NeuroLex IDnlx_anat_100313
TA98A14.1.08.940
TA25781
FMA62315
Anatomical terms of neuroanatomy

The vascular organ of lamina terminalis (VOLT), organum vasculosum of the lamina terminalis (OVLT), or supraoptic crest[1] is one of the four sensory circumventricular organs of the brain, the others being the subfornical organ, the median eminence, and the area postrema in the brainstem.[2]

Anteroventral third ventricle region

The OVLT, median eminence, and subfornical organ are interconnected with the mid-

ventral hypothalamus, and together these three structures surround the third ventricle, a complex often called the anteroventral region of the third ventricle ("AV3V" region).[2][3][4] This region functions in the regulation of fluid and electrolyte balance by controlling thirst, sodium excretion, blood volume regulation, and vasopressin secretion.[3][5]

Function

The OVLT is one of the four sensory circumventricular organs providing information to other brain regions (others are median eminence, subfornical organ, and area postrema).[2][6][7]

OVLT capillaries do not have a blood–brain barrier, and so neurons in this region can respond to circulating factors present in the systemic circulation.[2][5]

Neurons in the OVLT are

angiotensin II, which stimulates receptors in the VOLT and subfornical organ to complete a positive feedback loop.[5][8][9] These neurons also project to the median preoptic nucleus which is involved in controlling thirst.[2][5][8]

References

  1. ^ "Organum vasculosum". BrainInfo, University of Washington, Seattle.
  2. ^
    S2CID 18748366
    .
  3. ^
    S2CID 4781981
    .
  4. PMID 26578857
    .
  5. ^
    S2CID 13339562
    .
  6. S2CID 27789146
    .
  7. doi:10.1016/j.physbeh.2007.04.003
    .
  8. ^
    S2CID 43091000
    .
  9. ISBN 978-0-7020-3738-2
    .


Stub icon

This neuroanatomy article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Vascular_organ_of_lamina_terminalis&oldid=1211702889"