ADCK5
| ADCK5 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 8: 144.37 – 144.39 Mb | Chr 15: 76.46 – 76.48 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
ADCK5 (aarF domain containing kinase 5) is an enzyme that in humans is encoded by the ADCK5 gene. It is situated on chromosome 8 at the q24.3 location.
Function
ADCK5 is predicted to possess protein serine/threonine kinase activity and to be an integral component of the membrane.[5]
Genomic context
The ADCK5 gene is located on chromosome 8q24.3. The genomic sequence spans 20,154 base pairs from 144,373,088 to 144,393,242 on the GRCh38.p14 primary assembly. It consists of 19 exons.[5]
Expression
ADCK5 is ubiquitously expressed across various human tissues, with notable expression in the duodenum and small intestine, among others.[5]
Clinical significance
Research indicates that ADCK5 may have therapeutic implications in lung cancer.[6]
References
- ^ a b c ENSG00000285451 GRCh38: Ensembl release 89: ENSG00000173137, ENSG00000285451 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022550 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b c https://www.ncbi.nlm.nih.gov/gene/203054
- PMID 32277958.
