Ornidazole
QP51AA03 (WHO) | |
| Pharmacokinetic data | |
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| Metabolism | Via liver[1]: 1356 |
| Elimination half-life | 12-13 hours[1]: 1356 |
| Excretion | Urine (63%) and Feces (22%) |
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Ornidazole is an antibiotic used to treat
protozoan infections.[1]: 1368 A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin.[2]
Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated;[1]: 1368 however there are concerns of lower relative efficacy.[3]
It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities.[4]: 1261 has also been investigated for use in Crohn's disease after bowel resection.[5]
References
- ^ ISBN 978-0-7020-6285-8.
- ISBN 9780444894762.
- ISBN 978-1-4557-4801-3.
- ISBN 978-0-7020-6285-8
- PMID 15825069.
| Authority control databases: National |
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