SARS-CoV-2 Zeta variant

Source: Wikipedia, the free encyclopedia.

Zeta variant, also known as lineage P.2,

Gamma variant from Manaus.[1][2]

Under the simplified naming scheme proposed by the

variant of concern.[3] A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database.[4] As of July 2021, Zeta is no longer considered a variant of interest by the WHO.[5]

Mutations

The Zeta genome has 3

D614G, and V1176F, all of which are found in the virus's spike protein code.[6] According to the Centers for Disease Control and Prevention, F565L has been detected in some of the Zeta variant sequences, but not all.[7]

  • Amino acid mutations of SARS-CoV-2 Zeta variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[6]
    Amino acid mutations of SARS-CoV-2 Zeta variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[6]

Notes

  1. ^ A sub-lineage of B.1.1.28

References

  1. ^ "PANGO lineages Lineage P.2". COV lineages. Archived from the original on April 28, 2021. Retrieved January 28, 2021. P.2... Alias of B.1.1.28.2, Brazilian lineage
  2. PMID 33649194
    .
  3. ^ "Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings". Virological. January 12, 2021. Retrieved June 26, 2021.
  4. .
  5. ^ "Tracking SARS-CoV-2 variants". who.int. World Health Organization.
  6. ^ a b "Spike Variants: Zeta variant, aka P.2". covdb.stanford.edu. Stanford University Coronavirus Antiviral & Resistance Database. July 1, 2021. Retrieved July 5, 2021.
  7. ^ "SARS-CoV-2 Variant Classifications and Definitions". CDC.gov. Centers for Disease Control and Prevention. February 11, 2020. Retrieved July 5, 2021.