SARS-CoV-2 Zeta variant
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Variant of the SARS-Cov-2 virus
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Main article: Variants of SARS-CoV-2
Zeta variant, also known as lineage P.2,
Under the simplified naming scheme proposed by the
variant of concern.[3] A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database.[4] As of July 2021, Zeta is no longer considered a variant of interest by the WHO.[5]
Mutations
The Zeta genome has 3
D614G, and V1176F, all of which are found in the virus's spike protein code.[6] According to the Centers for Disease Control and Prevention, F565L has been detected in some of the Zeta variant sequences, but not all.[7]
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![Amino acid mutations of SARS-CoV-2 Zeta variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[6]](//upload.wikimedia.org/wikipedia/commons/thumb/8/83/SARS-CoV-2_Zeta_variant.svg/4586px-SARS-CoV-2_Zeta_variant.svg.png)
Amino acid mutations of SARS-CoV-2 Zeta variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[6]
![Amino acid mutations of SARS-CoV-2 Zeta variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[6]](/File:SARS-CoV-2_Zeta_variant.svg)
Notes
- ^ A sub-lineage of B.1.1.28
References
- ^ "PANGO lineages Lineage P.2". COV lineages. Archived from the original on April 28, 2021. Retrieved January 28, 2021.
P.2... Alias of B.1.1.28.2, Brazilian lineage
- PMID 33649194.
- ^ "Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings". Virological. January 12, 2021. Retrieved June 26, 2021.
- medRxiv 10.1101/2021.05.19.21257472v3.
- ^ "Tracking SARS-CoV-2 variants". who.int. World Health Organization.
- ^ a b "Spike Variants: Zeta variant, aka P.2". covdb.stanford.edu. Stanford University Coronavirus Antiviral & Resistance Database. July 1, 2021. Retrieved July 5, 2021.
- ^ "SARS-CoV-2 Variant Classifications and Definitions". CDC.gov. Centers for Disease Control and Prevention. February 11, 2020. Retrieved July 5, 2021.
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