Thienobenzodiazepine

Source: Wikipedia, the free encyclopedia.
Not to be confused with thienodiazepine or thienotriazolodiazepine.
General structure of thienobenzodiazepines. Core is highlighted by black and color. Grey depicts accessory functional groups.
General structure of thienobenzodiazepines. Core is highlighted by black and color. Grey depicts accessory functional groups.

Thienobenzodiazepine is a heterocyclic compound containing a diazepine ring fused to a thiophene ring and a benzene ring. Thienobenzodiazepine forms the central core of pharmaceutical drugs including atypical antipsychotic olanzapine (Zyprexa) and antimuscarinic telenzepine. Thienobenzodiazepines act relatively selectively at the α2 subunit of the GABAA receptor.[1]

References

  1. PMID 8822531
    – via PubMed.


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