Cyprazepam

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Cyprazepam
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • US: Unscheduled
Pharmacokinetic data
MetabolismHepatic
ExcretionRenal
Identifiers
  • 10-chloro-N-(cyclopropylmethyl)-3-hydroxy-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-1,6,8,10-tetraen-5-imine
JSmol)
  • ClC1=CC2=C(N/C(C[N+]([O-])=C2C3=CC=CC=C3)=N/CC4CC4)C=C1
  • InChI=1S/C19H18ClN3O/c20-15-8-9-17-16(10-15)19(14-4-2-1-3-5-14)23(24)12-18(22-17)21-11-13-6-7-13/h1-5,8-10,13H,6-7,11-12H2,(H,21,22) checkY
  • Key:UKFDTMNJMKWWNK-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Cyprazepam

amnestic
properties.

Synthesis

The lactam moiety in benzodiazepams is active towards nucleophiles and numerous analogues have been made by exploiting this fact.

Cyprazepam synthesis:[1]

For example, heating demoxepam with N-cyclopropylmethylamine leads to amidine formation, the minor tranquilizer cyprazepam.

See also

References

  1. ^ a b US 3138586, Wuest HM, "2-Cycloalkylamino Derivatives of 1,4-Benzodiazipines", issued 23 June 1964, assigned to Warner-Lambert Pharmaceutical Compay ; Chem. Abstr., 61: 7,032f (1964).
  2. S2CID 96638676. Archived from the original
    on 5 January 2013.
  3. ^ EP 1466628, Matthews B, Victor S, Nigel, Swindell C, "DHA-pharmaceutical agent conjugates", published 13 October 2004, assigned to American Regent Inc. 
  4. ^ "Harmonized Tariff Schedule of the United States (2009) - Supplement 1 - PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE" (PDF). USA: United States International Trade Commission. 2009. Archived from the original (PDF) on 31 July 2009. Retrieved 19 September 2009.
  5. S2CID 32956594
    .
  6. ^ World Health Organization (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). USA: Ministry of health, Syria. Retrieved 19 September 2009. [dead link]
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