Ciclotizolam

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Ciclotizolam
Ball-and-stick model of the ciclotizolam molecule
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 8-bromo-6-(o-chlorophenyl)-1-cyclohexyl-4H-5-triazolo(3,4-c)thieno(2,4-e)-1,4-diazepine
JSmol)
SMILES
  • Clc5ccccc5C/2=N/Cc1nnc(n1c3sc(Br)cc\23)C4CCCCC4
  • InChI=1S/C20H18BrClN4S/c21-16-10-14-18(13-8-4-5-9-15(13)22)23-11-17-24-25-19(26(17)20(14)27-16)12-6-2-1-3-7-12/h4-5,8-10,12H,1-3,6-7,11H2 checkY
  • Key:ZOSHXIXUCKESEG-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Ciclotizolam[1] (WE-973) is a drug which is a thienotriazolodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABAA receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy.[2][3]

See also

References

  1. ^ DE Patent 2445430
  2. PMID 2986988
    .
  3. .