Pyrazolam

Source: Wikipedia, the free encyclopedia.
Pyrazolam
rectal
Legal status
Legal status
Pharmacokinetic data
Elimination half-life17 hours
Identifiers
  • 8-Bromo-1-methyl-6-(pyridin-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
JSmol)
  • CC1=NN=C2CN=C(C3=NC=CC=C3)C3=CC(Br)=CC=C3N12
  • InChI=1S/C16H12BrN5/c1-10-20-21-15-9-19-16(13-4-2-3-7-18-13)12-8-11(17)5-6-14(12)22(10)15/h2-8H,9H2,1H3
  • Key:BGRWSFIQQPVEML-UHFFFAOYSA-N

Pyrazolam (SH-I-04)

Hoffman-La Roche in the 1970s.[3] It has since been "rediscovered" and sold as a designer drug since 2012.[4][5][6][7][8][9][excessive citations
]

Pyrazolam has structural similarities to alprazolam[10] and bromazepam. Unlike other benzodiazepines, pyrazolam does not appear to undergo metabolism, instead being excreted unchanged in the urine.[4]

Legal status

United Kingdom

In the UK, pyrazolam has been classified as a Class C drug by section 5 of the May 2017 amendment to The Misuse of Drugs Act 1971 along with several other designer benzodiazepine drugs.[11]

See also

References

  1. ^ (customs (prohibited imports) regulations 1956 - schedule 4, 1956)
  2. PMID 26682068
    .
  3. ^ US 3954728, Sternbach LH, Walser A, "Preparation of triazolo benzodiazepines and novel compounds", issued 4 May 1976, assigned to Hoffmann La Roche Inc. 
  4. ^
    S2CID 23273522
    .
  5. PMID 26043347
    .
  6. PMID 27366870
    .
  7. PMID 27685473
    .
  8. PMID 29582576
    .
  9. S2CID 247455284
    .
  10. PMID 5165540
    .
  11. ^ "The Misuse of Drugs Act 1971 (Amendment) Order 2017". legislation.gov.uk.
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