Dog health

Source: Wikipedia, the free encyclopedia.
Cavalier King Charles Spaniel with bandaged foot
A dog's injured leg

The health of dogs is a well studied area in veterinary medicine.

Dog health is viewed holistically; it encompasses many different aspects, including disease processes, genetics, and nutritional health, for example.

Infectious diseases that affect dogs are important not only from a veterinary standpoint, but also because of the risk to public health; an example of this is rabies. Genetic disorders also affect dogs, often due to selective breeding
to produce individual dog breeds. Due to the popularity of both commercial and homemade dog foods, nutrition is also a heavily studied subject.

Diseases

Some diseases and other health problems are common to both humans and dogs; others are unique to dogs and other animals. Dogs are susceptible to various diseases; similarly to humans, they can have diabetes, epilepsy, cancer, or arthritis.

Timely vaccination can reduce the risk and severity of an infection. The most commonly recommended viruses to vaccinate dogs against are:

A rabid dog

Infectious diseases

An infectious disease is caused by the presence of organisms such as viruses, bacteria, fungi, or parasites (either animalian or

vector such as a tick or mosquito.[2] Certain infectious diseases are a concern from a public health standpoint because they are zoonoses
(transmittable to humans)

Viral diseases

Viral diseases in dogs can be serious, especially in kennels.

Bacterial diseases

A number of Leptospira sp. bacteria atop a 0.1. µm polycarbonate filter

Bacterial diseases in dogs are usually not contagious from dog to dog; instead they are usually the result of wound colonization, opportunistic infections secondary to decreased resistance (often the result of viral infections), or secondary to other conditions (pyoderma secondary to skin allergies or pyometra secondary to cystic endometrial hyperplasia). These examples are not considered infectious diseases because they do not satisfy Koch's postulates – for example Staphylococcus intermedius, a commonly isolated bacteria from skin infections in dogs, would not cause pyoderma when introduced to a healthy dog. In all likelihood that type of bacteria is already present on the skin of a healthy dog.

There are some bacteria that are contagious from dog to dog. The most notable of these are Bordetella bronchiseptica, one of the causes of kennel cough, Leptospira sp, which cause leptospirosis,[3][4] and Brucella canis, cause of brucellosis in dogs. There are also common tick-borne bacterial diseases, including Lyme disease, ehrlichiosis, and Rocky Mountain spotted fever.

Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira. Humans and dogs become infected through contact with water, food, or soil containing urine from infected animals. This may happen by swallowing contaminated food or water or through skin contact, especially with mucosal surfaces, such as the eyes or nose, or with broken skin. In dogs, transmission most commonly occurs by drinking puddle, pond, or ditch water contaminated by urine from infected wildlife such as squirrels or raccoons. The liver and kidney are most commonly damaged by leptospirosis. Vasculitis can occur, causing edema and potentially disseminated intravascular coagulation (DIC). Myocarditis, pericarditis, meningitis, and uveitis are also possible sequelae.[5]

Ixodes scapularis

Brucellosis in dogs is caused by Brucella canis. It is a sexually transmitted disease, but can also be spread through contact with aborted fetuses. The most common sign is abortion during the last trimester or stillbirth. Other symptoms include inflammation of the intervertebral disc and eye (uveitis), and inflammation of the testicle (orchitis) and prostate (prostatitis) in males.[6]

Rhipicephalus sanguineous.[8]

Fungal diseases

One of the most common fungal diseases in dogs is

antifungal drugs such as griseofulvin or itraconazole. Infection can spread to humans.[9]

Blastomyces dermatitidis

There are several fungal diseases that are systemic in nature, meaning they are affecting multiple body systems. Blastomycosis, caused by Blastomyces species including Blastomyces dermatitidis, is a fungal disease that affects both dogs and humans. It is transmitted through the inhalation of fungal spores. It is found mainly in the United States in the Mississippi River and Great Lakes areas. It has also been reported in four Canadian provinces; Saskatchewan, Manitoba, Ontario and Quebec. Signs include weight loss, cough, fever, enlarged lymph nodes, draining skin lesions, eye inflammation with discharge, blindness, and lameness. Because dogs are ten times more likely to become infected from the environment than humans, they are considered to be sentinels for the disease. Treatment requires a minimum 60–90-day course of oral antifungal medication or in severe cases intravenous antifungal injections.[10]

semi-arid regions of Central and South America, Mexico, and southwestern United States. Signs include weight loss, fever, cough, enlarged lymph nodes, and lameness.[12][13]

Parasites

parasites
in animals. External parasites, such as fleas, mites, ticks and mosquitoes can cause skin irritation and are often carriers of other diseases or of internal parasites.

External parasites
  • Fleas and ticks of various species can be acquired and brought home by a dog, where they can multiply and attack humans (and vice versa). These two parasites are particularly important to note, now that tick-borne Lyme disease has become endemic throughout a large area, in addition to other similar diseases such as Rocky Mountain spotted fever. Although dogs do not seem to be as susceptible to such diseases as humans, similar rickettsial diseases have been spread by dogs to humans through such mechanisms as a dog killing an infected rabbit, then shaking itself off in the house near enough to its owners to fatally infect most of the family.[14]
  • Various mites cause skin problems such as mange.
  • Mosquitos
  • Lice infestations (pediculosis) cause intense pruritus, scratching, and hair loss. The two species of chewing lice that affect dogs are Trichodectes canis and Heterodoxus spiniger. The dog sucking louse is Linognathus setosus.[15]
Internal parasites
Dirofilaria immitis heart worms in a dog's heart

Genetic diseases

Bilateral hip dysplasia

St. Bernards.[16]
sensory organs
ranging from deafness to fatal flaws.

Skin diseases

Canine atopy

Skin diseases are very common in dogs.

Endocrine diseases such as hypothyroidism and Cushing's syndrome can also manifest as skin problems like alopecia or recurring bacterial infections. Another class of integumentary malady is hygromas, a swelling typically on or near the elbow joint. Nutrition may also play a role in skin disease, as deficiencies in certain nutrients may result in scaling, redness, oiling, balding, and/or itching of the skin.[19](See dog skin disorders
for specific nutrients that impacts skin)

Physical elements of certain dog breeds also affect susceptibility of individuals to skin problems, such as wrinkled skin or excessive skin folds. For instance, skin-fold dermatitis is a skin infection more prevalent in breeds such as the bulldog, cocker spaniel, and English Springer spaniel.[19]

Orthopedic diseases

Orthopedic diseases in dogs can be developmental, hereditary, traumatic, or degenerative. Because of the active nature of dogs, injuries happen frequently. One of the most common of these is an

non-steroidal anti-inflammatory drugs
.

Hereditary orthopedic diseases are mainly found in purebred dogs. Hip dysplasia is a common problem that primarily affects larger breeds. Hip dysplasia is a defect in the shape of the hip joint which can, depending on the degree of hip luxation, be quite painful to the dog as it ages. Over time it often causes arthritis in the hips. Dysplasia can also occur in the elbow joint. Luxating patellas can be a problem for smaller breeds. It can cause lameness and pain in the hind legs.

Developmental orthopedic diseases include panosteitis and hypertrophic osteodystrophy. Panosteitis occurs in large and giant breed dogs usually between the age of five and fourteen months and manifests as fever, pain, and shifting leg lameness. Hypertrophic osteodystrophy is also seen in young large and giant breed dogs and is characterized by pain, lameness, fever, and swelling of the long bone metaphysis.

Tumors and cancer

Kangal
with cancer in the left foreleg
A 10-year-old female beagle with oral cancer

Both

perianal gland adenomas
.

Frequently seen cancers include

mast cell tumors (which are considered to be potentially malignant, even though they may have benign behavior),[20] and osteosarcoma
(bone cancer).

Certain breeds are more likely to develop particular tumors, larger ones especially. The

Scottish terriers have eighteen times the risk of mixed breed dogs to develop transitional cell carcinoma, a type of urinary bladder cancer.[22]

Gastrointestinal diseases

Due to the indiscriminate nature of a dog's appetite, gastrointestinal upset is a frequent occurrence in dogs. The most common symptoms are anorexia, vomiting, and diarrhea. Foreign body ingestion can lead to acute obstruction of the gastrointestinal tract, a very dangerous condition. Acute pancreatitis can also result from dietary indiscretion.

Bloat and gastric torsion

Standard Poodles and Irish Setters. The stomach twists on its supporting ligaments, sealing off the exits, and the contents begin to generate gas pressure which is very painful and rapidly causes shock and necrosis of large areas of stomach tissue. It can be fatal within a few hours. Dogs who have experienced bloat are very susceptible to recurrences. Treatment involves stabilization and abdominal surgery to tack the dog's stomach down to prevent recurrence (gastropexy).[23]

Eye diseases

Cherry eye

Eye diseases are common in dogs.

sudden acquired retinal degeneration, and cherry eye. Injury to the eye can result in corneal ulcers
.

The frequency of bilateral glaucoma with a genetic base in purebred dogs is higher than in any species except humans.[24] Cataracts in dogs either have a genetic base or can also be caused by diabetes. Nuclear sclerosis resembles a cataract but is actually a normal age-related change.

Vestibular disease

Signs of vestibular disease include head tilt, circling,

intravenous fluids and nutrition; a light sedative
is sometimes administered, as the dog may be very stressed by the experience.

Heart disease

Older, small breeds of dogs are prone to

congestive heart failure caused by valvular disease. A major veterinary study, called the QUEST study (QUality of life and Extension of Survival Time), published in September 2008 found that dogs with congestive heart failure receiving pimobendan plus furosemide had significantly better survival outcomes than those receiving benazepril (an ACE inhibitor) plus furosemide.[26] However, ACE inhibitors and pimobendan have different mechanisms of action, and many veterinary cardiologists recommend they be used concurrently. Within the past decade, a new surgical technique has been developed for mitral valve repair that replaces or strengthens the mitral valve chords with polytetrafluoroethylene (PTFE) prostheses and tightens the mitral valve ring to reduce or eliminate regurgitation.[27][28][29][30]

ventricular arrhythmias. Boxer dogs are predisposed to a unique cardiomyopathy with clinical and histological changes analogous to human arrhythmogenic right ventricular cardiomyopathy (ARVC).[31] The disease has been termed "Boxer cardiomyopathy" or "Boxer ARVC", and is characterized by development of ventricular tachyarrhythmias.[32] Affected dogs are at risk of syncope and sudden cardiac death.[31] Myocardial failure and congestive heart failure are rare manifestations of this disease.[32]

In 2018, the U.S. Food and Drug Administration (FDA) issued a report citing a possible link between certain diets and canine dilated cardiomyopathy (DCM) in dog breeds without the genetic predisposition. Researchers at University of California, Davis School of Veterinary Medicine announced the results of their own study in early 2019, confirming the connection and identifying a particular concentration found among Golden Retrievers. Diet-related DCM is associated with grain-free and/or legume-rich diets, as well as "boutique" dog foods containing exotic ingredients (such as bison or kangaroo meat). In the treatment of dietary DCM, food change and taurine supplementation is typically indicated, in addition to traditional medical treatments as needed.

Other diseases and psychological issues

Other diseases affecting dogs include

immune-mediated thrombocytopenia, characterized by destruction of platelets by the immune system. Clinical signs include bruising and petechiae (pinpoint bruising, often seen in the mouth). Common reproductive diseases include pyometra (distension of the uterus with pus), mammary tumors, and benign prostatic hyperplasia
.

Psychological anxieties affecting dogs include noise phobia and separation anxiety.

Toxic substances

Some common sources of toxins that pets encounter include some plants,[33] human medications and cosmetics,[34] cleaning products,[34] and even some foods.[35]

Dangerous foods

Some foods consumed safely by humans are harmful to dogs:

Chocolate

Cocoa within chocolate contains

LD50) is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg.[38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended to induce vomiting within two hours of ingestion. Treatment protocol also includes intravenous fluid therapy and/or administration of activated charcoal.[38] Large breeds are less susceptible to chocolate poisoning, but can still die after eating four ounces[39]
of chocolate.

Carob treats are often available as dog treats; these are unrelated to chocolate and are safe.

Grapes and raisins

Grapes and raisins can cause acute

renal tubular necrosis.[45]

Onions

Onions cause hemolytic anemia in dogs and cats.[46][38] Allyl propyl disulfide has been reported as being considered to be the main cause of onion poisoning in dogs.[46] Alkyl thiosulfate and N-propyl disulfide have also been implicated. Thiosulfate levels are not affected by cooking or processing. Occasional exposure to small amounts is usually not a problem, but continuous exposure to even small amounts can be a serious threat.[38]

Plants in the genus Allium (onions, scallions, garlic, leek, chives, etc.) in general contain varying levels of organosulfoxides compounds including the two mentioned above. These chemicals are responsible for their signature spicyness, but also causes oxidative damage to red blood cells of dogs and cats. Poisoning have been reported from many such plants, with symptoms ranging from diarrhea and vomiting to pale gums and hemolysis.[47]

Nutmeg

neurotoxic to dogs and causes seizures, tremors, and nervous system disorders which can be fatal. Nutmeg's rich, spicy scent is attractive to dogs which can result in a dog ingesting a lethal amount of this spice. Eggnog and other food preparations which contain nutmeg should not be given to dogs.[48][49][50]

Macadamia nuts

Macadamia nuts can cause non-fatal stiffness, tremors, hyperthermia, and abdominal pain.[51]
The exact mechanism is not known. Most dogs recover with supportive care when the source of exposure is removed.

Hops

Yeast

Ingestion of yeast, for example in uncooked bread dough, can cause intestinal obstruction. The yeast can also cause fermentation internally, resulting in ethanol (alcohol) poisoning.[53]

Xylitol

Xylitol is a sugar substitute used in chewing gum, chewable vitamins, candy, toothpaste, and other products. Although a small preliminary study[54] indicated xylitol may be safe for dogs, other studies show significant toxicity.[55] There have been cases of foods, candies and gums containing xylitol causing toxic or even fatal liver damage in dogs.[56][57][58] Ingestion may cause hypoglycemia.[38]

Avocado

Avocado leaves, bark, skin, and pit are known to be harmful to a wide range of animals, including dogs and cats. Death can occur from a sufficiently high dose. The flesh of the fruit is not generally considered toxic to the two animals.[59]

Common household substances

Some common household chemicals are particularly dangerous to dogs:

Antifreeze (ethylene glycol)
Alcohols
Isopropanol, methanol (common in household products), and ethanol (common in alcoholic beverages and rotten fruits) are all toxic to dogs. Isopropanol found in rubbing alcohol has twice the toxicity of ethanol; however, methanol found in windshield washer fluid does not have the same retinal and neuronal toxicity on dogs as it does to humans and primates due to the differences in the way its metabolite formic acid is processed.[60]
The effect of ethanol on dogs and cats is similar to its effect on humans, also causing intoxication. Death is unlikely given supportive care (only one death is known). Ethanol is also an antidote for ethylene glycol poisoning.[47]
Mouse and rat poison
, anticoagulant type
Rodenticide is commonly found in the house or garage. This anticoagulant class of poison works by depleting stores of Vitamin K in the body; without these stores, blood cannot clot properly. Clinical signs of poisoning include depression, weakness, difficulty breathing, bruising, and bleeding from any part of the body. These clinical signs often take 3 to 4 days to appear. A blood test will confirm that the blood is not clotting properly. If the poison has only recently been ingested (within 2 to 3 hours), the dog should be given apomorphine or hydrogen peroxide to induce vomiting. Activated charcoal can be given to absorb any remaining poison in the gastrointestinal tract. Then the dog is given Vitamin K supplementation for 3 to 4 weeks, depending on the type of poison. At the end of treatment, the clotting times should be tested again. The prognosis is good in these cases. However, if the dog is already showing signs of poisoning, it is too late to try to remove the poison from the body. A whole blood transfusion or plasma is given to treat the anemia and to try to control bleeding. Vitamin K is also given. The prognosis is poor in these cases.
Mouse and rat poison, hypercalcemia type
Mouse and rat poisons containing
intravenous fluids (saline), diuretics, corticosteroids, and calcitonin
. Long term prognosis is good once the dog is stabilized.
Snail bait, metaldehyde type
Ingestion can cause anxiety, muscle twitching, seizures, rapid heart rate, dilated pupils, hypersalivation, vomiting, diarrhea, and high fever due to the
lavage, intravenous fluid administration, and/or administration of activated charcoal.[38]

Over-the-counter medications

Poisoning with pain medications is common.

Public health risks

Sarcoptes scabiei

Most diseases that affect dogs or humans are not transferable between the two species. Diseases that can be transmitted from animals to humans are termed

ringworm, caused in this case by Microsporum canis
.

Preventive medicine

Vaccinations

Vaccinations are an important preventive animal health measure. The specific vaccinations recommended for dogs varies depending on geographic location, environment, travel history, and the activities the animal frequently engages in. In the United States, regardless of any of these factors, it is usually highly recommended that dogs be vaccinated against rabies, canine parvovirus, canine distemper, and infectious canine hepatitis (using canine adenovirus type 2 to avoid reaction). The decision on whether to vaccinate against other diseases, including leptospirosis, Lyme disease, Bordetella bronchiseptica,

parainfluenza virus, and canine coronavirus
, should be made between an owner and a veterinarian, taking into account factors specific to the dog.

Dentistry

dental scaling and polishing. Cavities
are uncommon in dogs.

Heartworm, flea or tick preventives

Once-a-month topical products and oral medications are the most commonly used products to kill and prevent heartworm infection and flea or tick infestations.

Nutrition and obesity

Human food such as ice cream can lead to ill health and obesity in dogs.

Feeding table scraps to a dog is generally not recommended, at least in excess. Just as in humans, a dog's diet must consist of the appropriate mix of nutrients, carbohydrates, and proteins to give them the minerals and vitamins that they need. Dogs get ample correct nutrition from their natural, normal diet; wild and feral dogs can usually get all the nutrients needed from a diet of whole prey and raw meat. In addition, a human diet is not ideal for a dog: the concept of a "balanced" diet for a facultative carnivore like a dog is not the same as in an omnivorous human. Dogs will usually eat all the scraps and treats they are fed: usually too much food. While not all human delicacies are acutely toxic to dogs (see above), many have the same chronically unfortunate results as they do for humans.

This Australian Cattle Dog's obesity poses a health risk for the dog.

arterial consequences of obesity than humans are). According to a study published in the Journal of Veterinary Internal Medicine, the prevalence of obesity in dogs is between 22 and 40 percent.[65]

Obesity may also be caused by some diseases, such as Cushing's disease or hypothyroidism.[66]

Dog treats

Dog treats are often given to pets as a reward or just to let them chew on a bone, which works their jaw muscles and helps keep their teeth clean.[67] Although dog treats carry high benefits for dogs' teeth, they can also be a source of problems like obesity when given excessively, especially human table scraps.

The type of food given directly affects the tendency of a dog to become overweight. Table scraps, treats, and even premium high-energy dog foods can contribute to obesity.

calories
.

Coprophagia

Some dogs may attempt to consume feces. Some consume their own or other dogs' feces; others seem to prefer cat feces (which, due to the feline digestive system,[69] are high in protein and consumed by many animals in the wild.) This can be harmful if the feces has any pathogens or parasites or contain excreted drugs.

Vitamins and supplements

It is not yet clear whether or not

vitamins and supplements should be administered in dogs—opinions among veterinarians vary widely. While some think that vitamins and supplements are necessary and can improve the health of a dog, others believe that they are unnecessary and may harm the dog. According to the U.S. Food and Drug Administration
(FDA), dogs receive a complete and balanced diet from the commercially processed dog food alone. Pet owners who give their dogs homemade diets may incorporate extra vitamins and supplements.

Between approximately 10 and 30 percent of dogs in the United States receive nutritional supplements.[70] A survey of U.S. pet owners in 2006 found that the most commonly used supplements were multivitamins and chondroprotective agents.[71]

Overdoses of vitamins can be harmful in dogs. As an example,

muscular atrophy, loss of appetite and many other health-related problems
.

Reproductive health

Spaying and neutering

Spaying (females) and neutering (males) refers to the sterilization of animals, usually by removal of the male's testicles or the female's ovaries and uterus, to eliminate the ability to procreate and reduce sex drive. Neutering has also been known to reduce aggression in male dogs, but has been shown to occasionally increase aggression in female dogs.[73]

Animal control agencies in the United States and the

ASPCA advise that dogs not intended for further breeding should be spayed or neutered so that they do not have undesired puppies.[74]

Because of the overpopulation of dogs in some countries, puppies born to strays or as the result of accidental breedings often end up being killed in animal shelters. Spaying and neutering can also decrease the risk of hormone-driven diseases such as mammary cancer, as well as undesired hormone-driven behaviors. However, certain medical problems are more likely after surgery, such as urinary incontinence in females[75] and prostate cancer in males.[76] The hormonal changes involved with sterilization are likely to somewhat change the animal's personality, however, and some object to spaying and neutering as the sterilization could be carried out without the excision of organs.

It is not essential for a female dog to either experience a heat cycle or have puppies before spaying, and likewise, a male dog does not need the experience of mating before neutering.

Female cats and dogs are seven times more likely to develop

phytoestrogens in levels that could have biological effects when ingested longterm.[78]

See also

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External links