2-Oleoylglycerol

Source: Wikipedia, the free encyclopedia.
2-Oleoylglycerol
Names
IUPAC name
2-O-[(9Z)-Octadec-9-enoyl]glycerol
Systematic IUPAC name
1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate
Other names
2-Monoolein
Identifiers
3D model (
JSmol
)
ChemSpider
IUPHAR/BPS
UNII
  • InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9- checkY
    Key: UPWGQKDVAURUGE-KTKRTIGZSA-N checkY
  • CCCCCCCCC=CCCCCCCCC(=O)OC(CO)CO
Properties
C21H40O4
Molar mass 356.547 g·mol−1
Density 0.958 g/cm3
Hazards
Flash point > 113.0 °C (235.4 °F; 386.1 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

2-Oleoylglycerol (2OG) is a

diacylglycerol precursors. It is metabolized to oleic acid and glycerol primarily by the enzyme monoacylglycerol lipase (MAGL).[1] In 2011, 2OG was found to be an endogenous ligand to GPR119.[2] 2OG has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine.[2]

See also

References

  1. PMID 12136125
    .
  2. ^
    PMID 21778222
    .


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