Impact of alcohol on aging

Source: Wikipedia, the free encyclopedia.

The impact of alcohol on aging is multifaceted. Evidence shows that alcoholism or chronic

depression.[2] On the other hand, research also shows that drinking moderate amounts of alcohol may protect healthy adults from developing coronary heart disease.[3] The American Heart Association cautions people not to start drinking, if you are not already drinking. [4]

Brain

Alcohol is a potent

HPA axis, causing glucocorticoid secretion and thus elevating levels of stress hormones in the body. Chronic exposure to these hormones results in an acceleration of the aging process, which is associated with "gradual, but often dramatic, changes over time in almost every physiological system in the human body. Combined, these changes result in decreased efficiency and resiliency of physiological function." Chronic stress and chronic heavy alcohol use cause a similar premature aging effect, including nerve cell degeneration in the hippocampus.[1]

Heart

According to the National Institutes of Health, researchers now understand that drinking moderate amounts of alcohol can protect the hearts of some people from the risks of coronary artery disease.[7] But, it's not possible to predict in which people alcoholism will become a problem. Given these and other risks, the American Heart Association cautions people not to start drinking. [8]

Life expectancy

A study published in August 2010 in the journal, “Alcoholism: Clinical and Experimental Research,” followed 1,824 participants between the ages of 55 and 65 and found that even after adjusting for all suspected covariates, abstainers and heavy drinkers continued to show increased mortality risks of 51 and 45%, respectively, compared to moderate drinkers.[9] A follow-up study lists several cautions in interpreting the findings. For example, the results do not address nor endorse initiation of drinking among nondrinkers, and persons who have medical conditions which would be worsened by alcohol consumption should not drink alcohol.[10] Additional research suggests that the reasons for alcohol abstinence may be a determining factor in the outcomes for abstainers: those who do not drink because of existing medical conditions or because of previous substance use disorder issues have the highest rates of early death among the abstainers. Other groups of abstainers, such as those who do not drink because of family upbringing or moral/religious reasons, have mortality risks that are as low as those who drink in moderation. [11]

Demographics

Excessive alcohol consumption, especially of

former Soviet Union.[12][13]

See also

  • Alcohol dementia

References

  1. ^ a b Alcohol, Aging, and the Stress Response, RL Spencer and KE Hutchison, Alcohol Research & Health, Vol. 23, No. 4, 1999 ...alcohol-related overactivity of the HPA axis and the resulting elevated cortisol levels may contribute to premature or exaggerated aging in many people with a long history of alcohol abuse.
  2. S2CID 24586529
    .
  3. ^ National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, "Understanding the impact of alcohol on human health and well-being."
  4. ^ "Is drinking alcohol part of a healthy lifestyle?".
  5. ^ Thomas P. Beresford; Edith Lisansky Gomberg; Edith S. Gomberg. Alcohol and Aging. p. 85.
  6. ^ Alcohol and Aging - Alcohol Alert No. 40-1998
  7. ^ "Beyond Hangovers: understanding alcohol’s impact on your health," NIH Publication No. 10–7604, revised May 2011
  8. ^ "Is drinking alcohol part of a healthy lifestyle?".
  9. PMID 20735372.{{cite journal}}: CS1 maint: multiple names: authors list (link
    )
  10. PMID 22152665
    .
  11. ^ Rogers, R.G., Krueger, P.M., Miech, R. et al. Popul Res Policy Rev (2013) 32: 325. https://doi.org/10.1007/s11113-013-9268-7
  12. PMID 30113627
    .
  13. doi:10.15185/izawol.168
    . Retrieved 29 August 2020.
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