Adenomyomatosis
Adenomyomatosis | |
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Micrograph showing Rokitansky–Aschoff sinus. H&E stain. |
Adenomyomatosis is a benign condition characterized by hyperplastic changes of unknown cause involving the wall of the gallbladder.[1] Adenomyomatosis is caused by an overgrowth of the mucosa, thickening of the muscular wall, and formation of intramural diverticula or sinus tracts termed Rokitansky–Aschoff sinuses, also called entrapped epithelial crypts.[citation needed]
Pathophysiology
a The fundus of the gallbladder wall was thickened and the GB wall was obscure.
b The intramural echogenic foci were detected by high frequency transducer.
c CEUS—arterial phase (22 s) —heterogeneous hyper-enhancement and wall was intact.
d CEUS—venous phase (34 s) the anechoic spaces were more clear.
Rokitansky–Aschoff sinuses
Rokitansky–Aschoff sinuses are pseudodiverticula or pockets in the wall of the
Rokitansky–Aschoff sinuses are not of themselves considered abnormal but they can be associated with cholecystitis.[5]
They form as a result of increased pressure in the gallbladder and recurrent damage to the wall of the gallbladder.[6]
Associations
Black pigment gallstones can form in Rokitansky–Aschoff sinuses of the gallbladder after the fourth to fifth decades of life in absence of the typical risk factors for bilirubin supersaturation of bile.
Diagnosis
On CT scan, it may show rosary sign, showing mucosal epithelium with intramural diverticula.[8]
Eponym
Rokitansky–Aschoff sinuses are named after
See also
- Cholecystectomy
- Strawberry gallbladder
- Diverticulum
- Hyperplasia
- Gallbladder