Clorgiline

Source: Wikipedia, the free encyclopedia.
Clorgiline
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine
JSmol)
  • Clc1cc(Cl)ccc1OCCCN(CC#C)C
  • InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3 checkY
  • Key:BTFHLQRNAMSNLC-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Clorgiline (

affinity to the σ1 receptor (Ki = 3.2 nM)[3][5] and with very high affinity to the I2 imidazoline receptor (Ki = 40 pM).[6]

Clorgiline is also a

multiple fungicide resistance.[7]

References

  1. ^
    ISBN 978-1-4757-2085-3
    .
  2. ISBN 978-94-011-4439-1
    .
  3. ^
    ISBN 978-0-7484-0063-8
    .
  4. PMID 9564606
    .
  5. ISBN 978-0-12-376350-1
    .
  6. PMID 8828003
    .
  7. ^ a b
    •  • Prasad R, Banerjee A, Shah AH (February 2017). "Resistance to antifungal therapies". Essays in Biochemistry. 61 (1).
      S2CID 21170509
      .
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