List of antiviral drugs
Antiviral drugs are different from antibiotics. Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as COVID-19. Antiviral drugs prescribed to treat COVID-19 are not approved or authorized to treat flu.[1]
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Antiviral | Use | Manufacturer | Component | Type | Year approved |
---|---|---|---|---|---|
Abacavir | HIV | ViiV Healthcare | reverse transcriptase inhibitor (NRTI)
|
1998 | |
Acyclovir (Aciclovir)
|
guanosine analogue RTI | 1981 | |||
Adefovir | Hepatitis B[3] | Gilead Sciences | RTI | 2002 ( FDA), 2003 (EU )
| |
Amantadine | Influenza | Influenza A virus M2 proton channel antagonist | |||
Ampligen
|
Avian Influenza
|
double-stranded RNA
|
|||
Amprenavir (Agenerase) | HIV | Protease inhibitor (PI) | |||
Umifenovir (Arbidol) | Influenza | Hemagglutinin inhibitor | |||
Atazanavir | HIV | PI | |||
) | HIV |
|
|||
Baloxavir marboxil (Xofluza)[4] | Influenza A/B | Cap snatching endonuclease inhibitor | 2018 | ||
) | HIV |
|
|||
Boceprevir | Hepatitis C genotype 1[5] | Schering-Plough, then Merck Group | Protease inhibitor |
| |
Bulevirtide | Hepatitis D/B | Sodium/bile acid cotransporter inactivator | |||
Cidofovir | AIDS | Viral DNA Polymerase inhibitor
|
|||
Cobicistat (Tybost)[6] | HIV | human CYP3A protein inhibitor | |||
Combivir (Lamivudine/Zidovudine )
|
HIV | ||||
Daclatasvir (Daklinza) | Hepatitis C | NS5A inhibitor
|
|||
Darunavir | HIV | antiretroviral | HIV PI | ||
Delavirdine | HIV | antiretroviral | NNRTI | ||
Descovy (Emtricitabine/tenofovir alafenamide)
|
Hepatitis B |
|
|||
Didanosine | HIV | Adenosine analogue RTI | |||
Docosanol
|
Herpes Simplex | Entry inhibitor | |||
Dolutegravir | HIV | Integrase inhibitor | |||
Doravirine (Pifeltro)[7] | HIV | NNRTI | |||
Edoxudine | Herpes Simplex | Thymidine analogue inhibitor | |||
Efavirenz | HIV | Mylan | NNRTI | 1998 | |
Elvitegravir | HIV | Gilead Sciences | Integrase inhibitor |
| |
Emtricitabine | HIV | Gilead Sciences | NRTI | 2003 | |
Enfuvirtide | HIV | Entry inhibitor | 2003 | ||
Ensitrelvir | COVID-19 | Shionogi | 3C-like protease inhibitor | ||
Entecavir | HIV | NRTI | 2005 | ||
Etravirine (Intelence)[8] | HIV | NNRTI | 2008 | ||
Famciclovir | Herpes Zoster
|
Guanosine analogue | 1994 | ||
Fomivirsen | AIDS | Anti-sense oligonucleotide | Anti-sense |
| |
Fosamprenavir | HIV | ViiV Healthcare | Amprenavir pro-drug
|
2003 (FDA), 2004 (EMA) | |
Foscarnet | Herpes | DNA polymerase inhibitor
|
1991 | ||
Ganciclovir (Cytovene)[9] | Cytomegalovirus (CMV)[10] | Competitive nucleoside analogue dGTP inhibitor | 1988 | ||
Ibacitabine | Herpes labialis
|
||||
Ibalizumab (Trogarzo)[11] | HIV | Entry inhibitor | 2018 | ||
Idoxuridine | Herpes | dU analogue inhibitor | 1962 | ||
Imiquimod | Basal cell carcinoma, Actinic keratosis
|
Opioid growth factor receptor (OGFr) agonist | 1997 | ||
Inosine pranobex | Herpes Simplex | Thymus hormone immunostimulant | |||
Indinavir | HIV | PI | 1996 | ||
Lamivudine | HIV | cytidine analogue RTI | |||
Letermovir (Prevymis)[12] | Cytomegalovirus (CMV) | ||||
Lopinavir | HIV | ||||
Loviride | HIV | ||||
Maraviroc | HIV | entry inhibitor | |||
Methisazone
|
Smallpox | ||||
Molnupiravir | COVID-19 | viral RNA polymerase inhibitor | |||
Moroxydine | Influenza | ||||
Nelfinavir | HIV | ||||
Nirmatrelvir/ritonavir (Paxlovid) | COVID-19 | Pfizer | 3C-like protease inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir) | ||
Nevirapine | HIV | non- reverse transcriptase inhibitor
|
|||
Nitazoxanide | Broad-spectrum antiviral
|
thiazolide | |||
Norvir
|
HIV | ||||
Oseltamivir (Tamiflu)[13] | Influenza | neuraminidase inhibitor | |||
Penciclovir | Herpes | ||||
Peramivir | Influenza | ||||
Penciclovir | Herpes | ||||
Peramivir (Rapivab)[14] | Influenza | ||||
Pleconaril | Picornavirus | Schering-Plough | |||
Podophyllotoxin | Genital wart | ||||
Raltegravir | HIV | Integrase inhibitor | |||
Remdesivir | COVID-19 | viral RNA polymerase inhibitor | |||
Ribavirin | Hepatitis C[15] | reverse transcriptase inhibitor
|
|||
Rilpivirine (Edurant)[16] | HIV | ||||
Rilpivirine | HIV | ||||
Rimantadine | Influenza A
|
M2 proton channel antagonist | |||
Ritonavir | HIV | HIV-1 protease inhibitor | |||
Saquinavir | HIV | ||||
Simeprevir (Olysio) | Hepatitis C | ||||
Sofosbuvir | Hepatitis C[17] | reverse transcriptase inhibitor
|
|||
Stavudine | HIV | ||||
Taribavirin (Viramidine) | Hepatitis Syndromes in which Ribavirin is active[18] | ||||
Telaprevir | Hepatitis C | ||||
Telbivudine (Tyzeka) | Hepatitis B | ||||
Tenofovir alafenamide | Hepatitis B | ||||
Tenofovir disoproxil | Hepatitis B, HIV[19] | ||||
Tipranavir | HIV | ||||
Trifluridine | Eyes related Herpes | ||||
Trizivir
|
HIV | ||||
Tromantadine | Herpes Simplex | ||||
Truvada
|
HIV | ||||
Umifenovir | Influenza | ||||
Valaciclovir (Valtrex)[20] | Herpes Simplex/Zoster | ||||
Valganciclovir (Valcyte)[21] | Cytomegalovirus (CMV) | ||||
Vicriviroc | HIV-1
|
Schering-Plough | pyrimidine CCR5 entry inhibitor | ||
Vidarabine | Herpes Simplex, Varicella Zoster
|
||||
Zalcitabine | HIV | ||||
Zanamivir (Relenza)[22] | Influenza A, Influenza B | ||||
Zidovudine | HIV[23] | Antiretroviral |
References
- ^ "What You Should Know about Flu Antiviral Drugs". 15 December 2022.
- ^ "Acyclovir". The American Society of Health-System Pharmacists. Archived from the original on 2015-01-05. Retrieved Jan 1, 2015.
- PMID 12606735.
- ^ "Xofluza- baloxavir marboxil tablet, film coated". DailyMed. 28 October 2019. Retrieved 21 September 2020.
- PMID 18408458. S2CID 43762307
- ^ "Tybost- cobicistat tablet, film coated". DailyMed. 27 August 2020. Retrieved 21 September 2020.
- ^ "Pifeltro- doravirine tablet, film coated". DailyMed. 10 October 2019. Retrieved 21 September 2020.
- ^ "Intelence- etravirine tablet". DailyMed. 9 June 2020. Retrieved 21 September 2020.
- ^ "Cytovene IV- ganciclovir sodium injection, powder, lyophilized, for solution". DailyMed. 19 June 2020. Retrieved 21 September 2020.
- ISBN 0-9757919-2-3
- ^ "Trogarzo- ibalizumab injection, solution". DailyMed. 8 April 2020. Retrieved 21 September 2020.
- ^ "Prevymis- letermovir tablet, film coated PREVYMIS- letermovir injection, solution". DailyMed. 23 March 2020. Retrieved 21 September 2020.
- ^ "Tamiflu- oseltamivir phosphate capsule TAMIFLU- oseltamivir phosphate powder, for suspension". DailyMed. Retrieved 21 September 2020.
- ^ "Rapivab- peramivir solution". DailyMed. 3 August 2020. Retrieved 21 September 2020.
- ^ "Rebetol, Ribasphere (ribavirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 28 February 2014. Retrieved 23 February 2014.
- ^ "Edurant- rilpivirine hydrochloride tablet, film coated". DailyMed. 8 June 2020. Retrieved 21 September 2020.
- PMID 25387551.
- PMID 16293677
- ^ "Tenofovir Disoproxil Fumarate". The American Society of Health-System Pharmacists. Archived from the original on 30 November 2016. Retrieved 29 November 2016.
- ^ "Valtrex- valacyclovir hydrochloride tablet, film coated". DailyMed. 10 December 2019. Retrieved 21 September 2020.
- ^ "Valcyte- valganciclovir tablet, film coated VALCYTE- valganciclovir hydrochloride powder, for solution". DailyMed. 9 August 2018. Retrieved 3 September 2022.
- ^ "Relenza- zanamivir powder". DailyMed. 21 June 2018. Retrieved 21 September 2020.
- ^ "Zidovudine". PubChem Public Chemical Database. NCBI. Archived from the original on October 25, 2012. Retrieved April 10, 2011.