BAY 60–6583

BAY 60–6583

Names
Preferred IUPAC name 2-({6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl}sulfanyl)acetamide
Other names BAY 60–6583
Identifiers
CAS Number	910487-58-0 Y
3D model ( JSmol )	Interactive image
ChemSpider	9892551
IUPHAR/BPS	3289
PubChem CID	11717831
UNII	UAT5472LHH Y
InChI InChI=1S/C19H17N5O2S/c20-7-14-17(12-3-5-13(6-4-12)26-9-11-1-2-11)15(8-21)19(24-18(14)23)27-10-16(22)25/h3-6,11H,1-2,9-10H2,(H2,22,25)(H2,23,24) Key: ZTYHZMAZUWOXNC-UHFFFAOYSA-N InChI=1/C19H17N5O2S/c20-7-14-17(12-3-5-13(6-4-12)26-9-11-1-2-11)15(8-21)19(24-18(14)23)27-10-16(22)25/h3-6,11H,1-2,9-10H2,(H2,22,25)(H2,23,24) Key: ZTYHZMAZUWOXNC-UHFFFAOYAY
SMILES N#Cc1c(SCC(N)=O)nc(N)c(C#N)c1-c3ccc(cc3)OCC2CC2
Properties
Chemical formula	C19H17N5O2S
Molar mass	379.435
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

BAY 60–6583 is a selective adenosine A_2B receptor agonist.^[1] It has been shown to provide protection from ischemia (lack of oxygen due to blocked blood supply) in both the heart and kidney of test animals,^[2][3] and has also been shown to be beneficial in treatment of acute lung and brain injury,^[4][5] as well as claimed anti-aging and anti-obesity effects,^[6] showing a range of potential applications for selective A_2B agonists.

References