Romifidine

Source: Wikipedia, the free encyclopedia.
Romifidine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		IV
ATCvet code
Legal status
Legal status
  • Veterinary use only
Identifiers
  • N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine
JSmol)
SMILES
  • C1CN=C(N1)NC2=C(C=CC=C2Br)F
  • InChI=1S/C9H9BrFN3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) ☒N
  • Key:KDPNLRQZHDJRFU-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Romifidine is a drug that is used in veterinary medicine as a sedative mainly in large animals such as horses,[1] although it may be used in a wide variety of species.[2][3] It is not used in humans, but is closely related in structure to the commonly used drug clonidine.

Romifidine acts as an

respiratory depression. It is often used alongside other sedative or analgesic drugs such as ketamine or butorphanol.[4][5] Yohimbine can be used as an antidote
to rapidly reverse the effects.

References

  1. PMID 16334961
    .
  2. PMID 17359455
    .
  3. S2CID 41300654
    .
  4. PMID 15663735
    .
  5. PMID 15581222
    .
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