Zatosetron

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Zatosetron
Clinical data
ATC code
  • none
Identifiers
  • 5-chloro-2,2-dimethyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1-benzofuran-7-carboxamide
JSmol)
  • CC1(Cc2cc(cc(c2O1)C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4C)Cl)C
  • InChI=1S/C19H25ClN2O2/c1-19(2)10-11-6-12(20)7-16(17(11)24-19)18(23)21-13-8-14-4-5-15(9-13)22(14)3/h6-7,13-15H,4-5,8-10H2,1-3H3,(H,21,23)/t13-,14+,15-
  • Key:SPKBYQZELVEOLL-QDMKHBRRSA-N
 ☒NcheckY (what is this?)  (verify)

Zatosetron (LY-277,359) is a drug which acts as an

antinauseant effects but without stimulating the rate of gastrointestinal transport.[2][3] It is also an effective anxiolytic in both animal studies and human trials,[4] although with some side effects at higher doses.[5][6]

See also

References

  1. PMID 2366187
    .
  2. PMID 1732548
    .
  3. S2CID 23486859
    .
  4. PMID 10211913
    .
  5. PMID 1867653
    .
  6. PMID 7768200
    .
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