Joachim Frank
Joachim Frank | |
---|---|
Spouse |
Carol Saginaw (m. 1983) |
Children | Ze Frank & Mariel Frank |
Awards |
|
Scientific career | |
Fields | University at Albany, Department of Biomedical Sciences Columbia University College of Physicians and Surgeons, Department of Biochemistry and Molecular Biophysics |
Thesis | Untersuchungen von elektronenmikroskopischen Aufnahmen hoher Auflösung mit Bilddifferenz- und Rekonstruktionsverfahren (1970) |
Doctoral advisor | Walter Hoppe |
Other academic advisors | Robert Glaeser, Robert Nathan |
Joachim Frank (German pronunciation:
Life and career
Frank was born in Siegen in the borough of Weidenau. After completing his Vordiplom (B.S.) degree in physics at the University of Freiburg (1963)[3] and his Diplom under Walter Rollwagen's mentorship at the Ludwig Maximilian University of Munich with the thesis "Untersuchung der Sekundärelektronen-Emission von Gold am Schmelzpunkt" (Investigation of secondary electron emission of gold at its melting point) (1967), Frank obtained his Ph.D. from the Technical University of Munich for graduate studies in Walter Hoppe's lab at the Max Planck Institut für Eiweiss- und Lederforschung (now Max Planck Institute of Biochemistry) with the dissertation Untersuchungen von elektronenmikroskopischen Aufnahmen hoher Auflösung mit Bilddifferenz- und Rekonstruktionsverfahren[4] (Investigations of high-resolution electron micrographs using image difference and reconstruction methods) (1970). The thesis explores the use of digital image processing and optical diffraction in the analysis of electron micrographs, and alignment of images using the cross-correlation function.
As a Harkness postdoctoral fellow, he had the opportunity to study for two years in the United States: with Robert Nathan at the Jet Propulsion Laboratory, California Institute of Technology; with Robert M. Glaeser at Donner Lab, University of California, Berkeley and with Benjamin M. Siegel at Cornell University, Ithaca, New York.[5][6][7] In the fall of 1972 he returned briefly to the Max Planck Institute of Biochemistry in Martinsried as research assistant, working on the theory of partial coherence in electron microscopy,[8] then, in 1973, he joined the Cavendish Laboratory, University of Cambridge as Senior Research Assistant under Vernon Ellis Cosslett.
In 1975 Frank was offered a position of senior research scientist in the Division of Laboratories and Research (now
Awards (selection)
- 1994 Humboldt Research Award of the Alexander von Humboldt Foundation[7]
- 2006 Fellow of the American Academy of Arts and Sciences[11]
- 2006 Member of the National Academy of Sciences[12]
- 2014 Benjamin Franklin Medal in Life Science of the Franklin Institute[13]
- 2017 Wiley Prize in Biomedical Sciences[14]
- 2017 Nobel Prize in Chemistry[15]
- 2018 Honorary Doctorate, University of Siegen (Germany)[16]
- 2018 Honorary Fellow of the Royal Microscopical Society
Selected publications
Books
- Frank, Joachim (2014), Found in Translation – Collection of Original Articles on Single-Particle Reconstruction and the Structural Basis of Protein Synthesis, Singapore: World Scientific Press, ISBN 978-981-4522-80-9.
- Herman, Gabor T.; Frank, Joachim (2014), Computational Methods for Three-Dimensional Microscopy Reconstruction, springer, ISBN 978-1-4614-9520-8.
- Frank, Joachim (2011), Molecular Machines in Biology: Workshop of the Cell, Cambridge: ISBN 978-0-521-19428-0.
- Glaeser, Robert M.; Downing, Ken; Chiu, Wah; Frank, Joachim; DeRosier, David (2007), Electron Crystallography of Biological Macromolecules, Oxford: ISBN 978-0-19-508871-7.
- Frank, Joachim (2006), Electron Tomography (2nd ed.), New York: Springer, ISBN 978-0-387-31234-7.
- Frank, Joachim (2006), Three-Dimensional Electron Microscopy of Macromolecular Assemblies (2nd ed.), Oxford: ISBN 978-0-19-518218-7.
Articles
- Frank, Joachim (2015). "Generalized single-particle cryo-EM – a historical perspective". Microscopy. 65 (1): 3–8. PMID 26566976.
- Frank, Joachim; Gonzalez, Jr., Ruben L. (2010). "Structure and dynamics of a processive Brownian motor: the translating ribosome". Annu. Rev. Biochem. 79: 381–412. PMID 20235828.
- Frank, Joachim; Spahn, Christian M.T. (2010). "The ribosome and the mechanism of protein synthesis". Rep. Prog. Phys. 69 (5): 1383–1417. S2CID 121917680.
- Frank, Joachim (2009). "Single-particle reconstruction of biological macromolecules in electron microscopy -- 30 years". Q. Rev. Biophys. 42 (3): 139–158. PMID 20025794.
References
- ^ Frank, Joachim (2017), Curriculum Vitae Archived October 9, 2017, at the Wayback Machine. Retrieved October 4, 2017.
- ^ "The Nobel Prize in Chemistry 2017". The Nobel Foundation. October 4, 2017. Retrieved October 6, 2017.
- ^ Entry in the University Archive Freiburg, Prüfungsausschuss für Diplom-Physiker B 11/593
- ^ Entry in the catalogue of the Deutsche Nationalbibliothek: DNB 482124628
- ^ "Joachim Frank, PhD | P&S; Research". Archived from the original on October 9, 2017. Retrieved October 5, 2017.
- ^ PMID 18056798.
- ^ a b "Archived copy" (PDF). Archived from the original (PDF) on October 9, 2017. Retrieved October 4, 2017.
{{cite web}}
: CS1 maint: archived copy as title (link) - ^ Frank, Joachim (1973), "The envelope of electron microscopic transfer functions for partially coherent illumination", Optik, 38: 519–539.
- ^ Wicher, Konrad (2006). History of the electron microscope: the high voltage electron microscope and beyond at the Division of Laboratories and Research/Wadsworth Center. Albany, New York: Wadsworth Center, New York State Department of Health. p. 149.
- PMID 1236029.
- ^ Book of Members 1780–present (PDF, 878 kB) at American Academy of Arts and Sciences (amacad.org); Retrieved February 23, 2017.
- ^ "Joachim Frank". nasonline.org. January 12, 2006. Retrieved February 23, 2017.
- ^ "Joachim Frank". fi.edu. December 12, 2014. Retrieved February 23, 2017.
- ^ "The 16th Annual Wiley Prize in Biomedical Sciences Awarded for Pioneering Developments in Electron Microscopy". newsroom.wiley.com. February 22, 2017. Archived from the original on October 4, 2017. Retrieved February 23, 2017.
- ^ "Nobel Prize in Chemistry Awarded for Cryo-Electron Microscopy". The New York Times. October 4, 2017. Retrieved October 4, 2017.
- ^ "Respect and Recognition". uni-siegen.de. April 17, 2018. Retrieved October 2, 2018.
Further reading
- Mossman, Kaspar (December 11, 2007). "Profile of Joachim Frank". Proceedings of the National Academy of Sciences of the USA. 104 (50): 19668–19670. PMID 18056798.
External links
- Frank Lab Archived March 25, 2021, at the Wayback Machine website
- List of Publications Archived December 24, 2020, at the Wayback Machine
- Joachim Frank publications indexed by Google Scholar
- Joachim Frank on Nobelprize.org including the Nobel Lecture on December 8, 2017 Single-Particle Reconstruction – Story in a Sample