Carl Ferdinand Cori

Source: Wikipedia, the free encyclopedia.
Carl Ferdinand Cori
Born(1896-12-05)December 5, 1896
Prague, Austria-Hungary
DiedOctober 20, 1984(1984-10-20) (aged 87)
Cambridge, Massachusetts, U.S.
NationalityAustrian-Hungarian
CitizenshipUnited States
Alma mater
  • First Faculty of Medicine, Charles University in Prague
Known forMetabolism of carbohydrates
Spouses
​
​
(m. 1920; died 1957)​
Anne Fitzgerald-Jones
​
​
(m. 1960)​
Children1
Awards
Scientific career
FieldsBiochemistry
InstitutionsWashington University in St. Louis
Websitenobelprize.org/medicine/laureates/1947/cori-cf-bio.html
Carl Cori with his wife and fellow-Nobelist, Gerty Cori, in 1947

Carl Ferdinand Cori, ForMemRS[1] (December 5, 1896 – October 20, 1984) was a Czech-American biochemist and pharmacologist. He, together with his wife Gerty Cori and Argentine physiologist Bernardo Houssay, received a Nobel Prize in 1947 for their discovery of how the glucose derivative glycogen (animal starch) is broken down and resynthesized in the body for use as a store and source of energy.[2][3][4] In 2004, both Coris were designated a National Historic Chemical Landmark in recognition of their work that elucidated carbohydrate metabolism.[5][6][7][8]

Education and early life

Carl Ferdinand Cori was born on December 5, 1896, in

Brüx – 1954, Vienna), a zoologist, and Maria Cori (née Lippich; 1870, Graz – 1922, Prague), a daughter of the Italian-Bohemian/Austrian physician Ferdinand Lippich [de; cs] (1838, Padua – 1913, Prague).[11][12]

The Cori family came from the

royal Bohemian crownland, (Monarchical Austria at the end of the 17th century). Carl Ferdinand's grandfather Eduard Cori (1812–1889)[13] was an administrative officer and beekeeper in Brüx, and his grandmother was Rosina Trinks (?–1909).[14] Carl Ferdinand's younger sister Margarete Cori (born 1905) was a lecturer in Prague and the wife of the Bohemian geneticist Felix Mainx (1900, Prague – 1983, Vienna).[15]

He grew up in

American constitutional lawyer and anti-feminist Phyllis Schlafly.[16]

Career

Carl was invited to

naturalized citizens
of the United States.

While at the Institute the Coris' research focused on

St. Louis, Missouri. Carl joined as professor of pharmacology and in 1942 was made professor of biochemistry. In St. Louis, the Coris continued their research on glycogen and glucose and began to describe glycogenolysis, identifying and synthesizing the important enzyme glycogen phosphorylase. For these discoveries, they received the Nobel Prize in Physiology or Medicine in 1947, making them the third ever married couple
to win the Nobel Prize.

Gerty died in 1957 and Carl married Anne Fitzgerald-Jones (1909-2006) in 1960. He stayed on at Washington University until 1966, when he retired as chair of the biochemistry department. He was appointed visiting professor of Biological Chemistry at

Salomé Glüecksohn-Waelsch of the Albert Einstein College of Medicine in New York, until the 1980s when illness prevented him from continuing.[17] In 1976, Carl received the Laurea honoris causa in Medicine from the University of Trieste
. Carl shares a star with Gerty on the St. Louis Walk of Fame.[18]

Awards and honors

In addition to winning the Nobel Prize, Cori won the

Foreign Member of the Royal Society (ForMemRS) in 1950.[1] The Carl Cori Endowed Professorship at Washington University is named in his honor, currently held by Colin Nichols.[23]

References

  1. ^
    PMID 11621260
    .
  2. PMID 18678102
    .
  3. PMID 11126836
    .
  4. S2CID 54345835
    .
  5. ^ "Carl and Gerti Cori and Carbohydrate Metabolism". American Chemical Society. Archived from the original on January 12, 2013. Retrieved June 6, 2012.
  6. PMID 320540
    .
  7. PMID 4896237
    .
  8. ^ Carl Ferdinand Cori — Biographical Memoirs of the National Academy of Sciences
  9. PMID 11616228
    .
  10. PMID 13315342
    .
  11. ^ Dolezal, Helmut. "Cori, Carl Isidor" in: Neue Deutsche Biographie 3 (1957), p. 360
  12. ^ [1], [2], [3]
  13. ^ [4], [5], commons:File:Anonym - Franz Eduard Cori.jpg
  14. ^ "Cori, Carl - Deutsche Biographie".
  15. ^ "Felix Mainx – Wien Geschichte Wiki". wien.gv.at. Archived from the original on 2017-02-02.
  16. ^ "Nobels All Around". National Review. 22 September 2012. Retrieved 13 March 2018.
  17. ^ Ginsberg, Judah (September 21, 2004). "Carl and Gerty Cori and Carbohydrate Metabolism". National Historic Chemical Landmark. American Chemical Society. Archived from the original on October 24, 2012. Retrieved August 28, 2012.
  18. ^ St. Louis Walk of Fame. "St. Louis Walk of Fame Inductees". stlouiswalkoffame.org. Archived from the original on 31 October 2012. Retrieved 25 April 2013.
  19. ^ "Reply to a parliamentary question" (PDF) (in German). p. 73. Retrieved 28 December 2012.
  20. ^ "Carl F. Cori". www.nasonline.org. Retrieved 2023-03-15.
  21. ^ "APS Member History". search.amphilsoc.org. Retrieved 2023-03-15.
  22. ^ "Carl Ferdinand Cori". American Academy of Arts & Sciences. 9 February 2023. Retrieved 2023-03-15.
  23. ^ Colin G. Nichols named Carl F. Cori Professor Archived 2016-01-07 at the Wayback Machine, Washington University in St. Louis, 2007-02-21

External links

  • Carl Cori on Nobelprize.org Edit this at Wikidata including the Nobel Lecture December 11, 1947 Polysaccharide Phosphorylase
Retrieved from "https://en.wikipedia.org/w/index.php?title=Carl_Ferdinand_Cori&oldid=1204424889"