SB-366791

SB-366791

Identifiers
IUPAC name (E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide
JSmol)	Interactive image
SMILES COC1=CC=CC(=C1)NC(=O)/C=C/C2=CC=C(C=C2)Cl
InChI InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ Key:RYAMDQKWNKKFHD-JXMROGBWSA-N

SB-366791 is a drug which acts as a potent and selective blocker of the TRPV1 ion channel. It has analgesic effects in animal studies, and is used in research into pain and inflammation.^[1][2][3]

• AMG-517
• AMG-9810
• Discovery and development of TRPV1 antagonists

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