Δ9-Tetrahydrocannabiorcol (Δ9-THCC, (C1)-Δ9-THC) is a
methyl group. Unlike THC and THCV, THCC has negligible affinity for the CB1 and CB2cannabinoid receptors because of the smaller methyl group and does not have psychoactive effects as a result, but conversely it is significantly more potent than THC or THCV as an activator of the TRPA1 calcium channel which plays an important role in pain perception,[2] and it has been shown to produce analgesic effects via activation of spinal TRPA1 channels. [3][4] THCC was studied by Roger Adams as early as 1942.[5]
