Dimetacrine

Source: Wikipedia, the free encyclopedia.
Dimetacrine
Skeletal formula of dimetacrine
Ball-and-stick model of the dimetacrine molecule
Clinical data
Trade namesIstonil, Istonyl, Linostil, Miroistonil
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)[1]
  • In general: ℞ (Prescription only)
Identifiers
  • 3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine
JSmol)
  • CC1(C2=CC=CC=C2N(C3=CC=CC=C31)CCCN(C)C)C

Dimetacrine (brand names Istonil, Istonyl, Linostil, Miroistonil), also known as dimethacrine and acripramine, is a

double-blind clinical trial against imipramine, dimetacrine was found to have lower efficacy in comparison and produced more weight loss and abnormal liver tests.[7][8]

Little is known about the pharmacology of dimetacrine,[9] but it can be inferred that it acts in a similar manner to other TCAs. If this is indeed the case, dimetacrine may induce severe cardiac toxicity in overdose (a side effect unique to the tricyclic class of antidepressants).

See also

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ISBN 0-412-54090-8
    .
  3. ISBN 978-0-87630-674-1
    .
  4. ISBN 978-3-527-31058-6
    .
  5. PMID 6008540
    .
  6. PMID 5756370
    .
  7. PMID 4149236
    .
  8. ISBN 0-8493-7774-9
    . Retrieved January 30, 2013.
  9. ^ "Dimetacrine". PubChem. U.S. National Library of Medicine. Retrieved 2023-11-03.