Thiopurine
Thioguanine
The thiopurine drugs are
organ transplant
recipients.
Metabolism is catalyzed by
S-methyltransferase and nudix hydrolase 15 (NUDT15).[1]
Litigation over patents covering diagnostic kits to monitor the dosing of these drugs led to a US Supreme Court case, Mayo Collaborative Services v. Prometheus Laboratories, Inc. that dramatically changed the nature of patent law in the United States.[2][3]
See also
- 6-Mercaptopurine(6-MP)
- 6-Thioguanine(6-TG)
- Azathioprine (AZA)
References
- PMID 18506437.
- ^ Supreme Court Decision. Mayo Collaborative Services v. Prometheus Laboratories, Inc., No. 10-1150, Slip Op. at 16. Decision
- ^ Gene Quinn, Killing Industry: The Supreme Court Blows Mayo v. Prometheus IP Watchdog (March 20, 2012).
External links