GPRC5B
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| Location (UCSC) | Chr 16: 19.86 – 19.89 Mb | Chr 7: 118.57 – 118.59 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
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G-protein coupled receptor family C group 5 member B is a protein that in humans is encoded by the GPRC5B gene.[5][6][7]
Function
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade.[7]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000167191 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000008734 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 10493829.
- PMID 10783259.
- ^ a b "Entrez Gene: GPRC5B G protein-coupled receptor, family C, group 5, member B".
Further reading
- Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN (2001). "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)". Genomics. 67 (1): 8–18. PMID 10945465.
External links
- "GPRC5 Receptors: RAIG2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2014-08-08. Retrieved 2008-12-04.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.