TAS2R31
| TAS2R31 | |||
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| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
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| UniProt | |||||||||
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| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 12: 11.03 – 11.03 Mb | Chr 6: 132.75 – 132.76 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Taste receptor, type 2, member 31, also known as TAS2R31, is a protein which in humans is encoded by the TAS2R31 gene.[5] This bitter taste receptor has been shown to respond to saccharin in vitro.[6]
TAS2R31 is also expressed in the
bronchodilation.[7]
Polymorphisms in this gene have been associated with the perceived bitterness of sweetener acesulfame potassium.[8]
See also
References
- ^ a b c ENSG00000263097, ENSG00000282256 GRCh38: Ensembl release 89: ENSG00000256436, ENSG00000263097, ENSG00000282256 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000053217 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: TAS2R31 taste receptor, type 2, member 31".
- PMID 15537898.
- PMID 20972434.
- PMID 23599216.
Further reading
- Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. PMID 11696554.
- Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. S2CID 37807140.
- Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. S2CID 20426192.
- Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. S2CID 718601.
- Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. S2CID 1542970.
- Pronin AN, Tang H, Connor J, Keung W (2005). "Identification of ligands for two human bitter T2R receptors". Chem. Senses. 29 (7): 583–93. PMID 15337684.
- Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. PMID 15496549.
- Kuhn C, Bufe B, Winnig M, Hofmann T, Frank O, Behrens M, Lewtschenko T, Slack JP, Ward CD, Meyerhof W (2005). "Bitter taste receptors for saccharin and acesulfame K." J. Neurosci. 24 (45): 10260–5. PMID 15537898.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.