TAAR8
| TAAR8 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 6: 132.55 – 132.55 Mb | Chr 10: 23.97 – 23.97 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Trace amine-associated receptor 8 is a
Gi/o-coupled.[8]
In humans, molecular modelling and docking experiments have shown that putrescine fits into the binding pocket of the human TAAR6 and TAAR8 receptors.[9]
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins, supplied by
OMIM[7]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000146385 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000100186 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 11574155.
- PMID 15718104.
- ^ a b "Entrez Gene: TAAR8 trace amine associated receptor 8".
- PMID 25391046.
- PMID 29324768.
Further reading
- Borowsky B, Adham N, Jones KA, Raddatz R, Artymyshyn R, Ogozalek KL, et al. (July 2001). "Trace amines: identification of a family of mammalian G protein-coupled receptors". Proceedings of the National Academy of Sciences of the United States of America. 98 (16): 8966–71. PMID 11459929.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.