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Protein-coding gene in the species Homo sapiens
TAS2R50 Identifiers Gene ontology
Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Wikidata Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene .[3] [4] [5] [6]
Function TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.[4] TAS2R10 .[6]
See also References Further reading
Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction" . J. Biol. Chem . 277 (1): 1–4. . Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol . 12 (4): 366–71. . Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways" . Cell . 112 (3): 293–301. . Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes" . Mol. Biol. Evol . 22 (3): 432–6. . Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates" . Genetics . 170 (1): 313–26. .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
