Source: Wikipedia, the free encyclopedia.
Protein-coding gene in the species Homo sapiens
NPY4R Identifiers Gene ontology
Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Wikidata Pancreatic polypeptide receptor 1 , also known as Neuropeptide Y receptor type 4 , is a protein that in humans is encoded by the PPYR1 gene .[3] [4] [5]
Selective Ligands Agonists Antagonists See also References External links Further reading
Balasubramaniam A (April 2002). "Clinical potentials of neuropeptide Y family of hormones". American Journal of Surgery . 183 (4): 430–434. . Parker E, Van Heek M, Stamford A (April 2002). "Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status". European Journal of Pharmacology . 440 (2–3): 173–187. . Benaim G, Villalobo A (August 2002). "Phosphorylation of calmodulin. Functional implications". European Journal of Biochemistry . 269 (15): 3619–3631. . Lundell I, Blomqvist AG, Berglund MM, Schober DA, Johnson D, Statnick MA, et al. (December 1995). "Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY" . The Journal of Biological Chemistry . 270 (49): 29123–29128. . Bard JA, Walker MW, Branchek TA, Weinshank RL (November 1995). "Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY" . The Journal of Biological Chemistry . 270 (45): 26762–26765. . Yan H, Yang J, Marasco J, Yamaguchi K, Brenner S, Collins F, Karbon W (May 1996). "Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors" . Proceedings of the National Academy of Sciences of the United States of America . 93 (10): 4661–4665. . Kawabe T, Muslin AJ, Korsmeyer SJ (January 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature . 385 (6615): 454–458. . Darby K, Eyre HJ, Lapsys N, Copeland NG, Gilbert DJ, Couzens M, et al. (December 1997). "Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14". Genomics . 46 (3): 513–515. . Hsieh-Wilson LC, Allen PB, Watanabe T, Nairn AC, Greengard P (April 1999). "Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1". Biochemistry . 38 (14): 4365–4373. . Smith FD, Oxford GS, Milgram SL (July 1999). "Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein" . The Journal of Biological Chemistry . 274 (28): 19894–19900. . Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR (May 2000). "PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts" . Cell . 101 (4): 365–376. . Connor JH, Weiser DC, Li S, Hallenbeck JM, Shenolikar S (October 2001). "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1" . Molecular and Cellular Biology . 21 (20): 6841–6850. . Cavadas C, Silva AP, Mosimann F, Cotrim MD, Ribeiro CA, Brunner HR, Grouzmann E (December 2001). "NPY regulates catecholamine secretion from human adrenal chromaffin cells" . The Journal of Clinical Endocrinology and Metabolism . 86 (12): 5956–5963. . Cox HM, Tough IR (March 2002). "Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa" . British Journal of Pharmacology . 135 (6): 1505–1512. . Wu DY, Tkachuck DC, Roberson RS, Schubach WH (August 2002). "The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity" . The Journal of Biological Chemistry . 277 (31): 27706–27715. .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
