TH-PVP
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TH-PVP is a substituted cathinone derivative which has been sold as a designer drug. It was first identified by a forensic laboratory in Hungary in 2015,[2] but has subsequently been found in numerous other countries around the world including Spain, Belgium, Poland, Turkey and Brazil.[3][4][5][6][7][8]
Pharmacological studies in vitro showed it to inhibit reuptake of the monoamine neurotransmitters, with about 10-fold selectivity for serotonin over norepinephrine and dopamine, whereas the drug did not induce monoamine release.[9] Despite its activity as a monoamine reuptake inhibitor, TH-PVP failed to produce stimulant effects in animals.[10]
See also
References
- ^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
- ^ "EMCDDA–Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA" (PDF). Archived (PDF) from the original on 2020-11-08. Retrieved 2019-12-08.
- PMID 27423024.
- S2CID 52281842.
- PMID 28640970.
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- S2CID 56176934.
- S2CID 208415740.
- PMID 30397775.
- PMID 30986635.