Desmethylsertraline
Source: Wikipedia, the free encyclopedia.
Chemical compound
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Pharmacokinetic data | |
Elimination half-life | 66 hours |
Excretion | urine |
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Desmethylsertraline (DMS), also known as norsertraline, is an
serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with about 5.5-fold preference for inhibiting serotonin reuptake relative to catecholamine reuptake.[2]
attention-deficit disorder, and eating disorders
, but has not been approved or marketed for any indication.
See also
- Desmethylcitalopram
- Desmethylvenlafaxine
- Didesmethylcitalopram
- Indatraline
- Lometraline
- Norfluoxetine
- Tametraline
References
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SNRIs Tooltip Serotonin–norepinephrine reuptake inhibitors | ||
NRIs Tooltip Norepinephrine reuptake inhibitors | ||
NDRIs Tooltip Norepinephrine–dopamine reuptake inhibitors | ||
NaSSAs Tooltip Noradrenergic and specific serotonergic antidepressants | ||
SARIs Tooltip Serotonin antagonist and reuptake inhibitors | ||
SMS Tooltip Serotonin modulator and stimulators | ||
Others |
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TCAs Tooltip Tricyclic antidepressants |
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TeCAs Tooltip Tetracyclic antidepressants | ||
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III