8-Carboxamidocyclazocine

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8-Carboxamidocyclazocine
Identifiers
  • (1S,10R,13R)-10-(Cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-triene-4-carboxamide
JSmol)
  • C[C@H]1[C@H]2Cc3ccc(cc3[C@]1(CCN2CC4CC4)C)C(=O)N
  • InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22)/t12-,17+,19-/m0/s1
  • Key:FAVQVALXVLMHLE-WILYLXEWSA-N
  (verify)

8-Carboxamidocyclazocine (8-CAC) is an

cocaine addiction.[2][3][4][5][6][7][8][9][10]

See also

  • Tianeptine – an atypical, selective μ-opioid receptor (MOR) full-agonist licensed for major depression since 1989.
  • Samidorphan – an opioid preferring the MOR, which is under development for major depression.

References

  1. ^ US Patent 6784187 8-carboxamido-2,6-methano-3-benzazocines
  2. PMID 11266156
    .
  3. S2CID 15864569
    .
  4. PMID 15588733
    .
  5. PMID 16942039
    .
  6. PMID 17935988
    .
  7. PMID 18417347
    .
  8. PMID 19091564
    .
  9. PMID 19282177
    .
  10. PMID 16353938
    .
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