Norbinaltorphimine

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Norbinaltorphimine
Clinical data
ATC code
  • none
Identifiers
  • 17,17'-(Dicyclopropylmethyl)-6,6',7,7'-6,6'-imino- 7,7'-bimorphinan-3,4',14,14'-tetrol
JSmol)
  • C1CC1CN2CC[C@]34[C@@H]5C6=C(C[C@]3([C@H]2CC7=C4C(=C(C=C7)O)O5)O)C8=C(N6)[C@H]9[C@@]12CCN([C@@H]([C@@]1(C8)O)CC1=C2C(=C(C=C1)O)O9)CC1CC1
  • InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 ☒N
  • Key:APSUXPSYBJVPPS-YAUKWVCOSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Norbinaltorphimine (nor-BNI or nBNI) is an

δ-opioid receptors,[1][2] although it is less selective in vivo than in isolated tissues.[3] nor-BNI blocks the effects of κ-opioid agonists in animal models,[4][5] and produces antidepressant[6] and anxiolytic-like effects.[2]

See also

References

  1. PMID 2882399
    .
  2. ^
    S2CID 22465963
    .
  3. PMID 2831070
    .
  4. PMID 2839664
    .
  5. PMID 2849679
    .
  6. PMID 15312181
    .


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