N-Phenethyl-14-ethoxymetopon

Source: Wikipedia, the free encyclopedia.
N-Phenethyl-14-ethoxymetopon
Identifiers
  • (5α)-14-Ethoxy-3-hydroxy-5-methyl-17-(2-phenylethyl)-4,5-epoxymorphinan-6-one
JSmol)
  • CCO[C@@]12CCC(=O)[C@]3([C@@]14CCN([C@@H]2CC5=C4C(=C(C=C5)O)O3)CCC6=CC=CC=C6)C
  • InChI=1S/C27H31NO4/c1-3-31-27-13-11-22(30)25(2)26(27)14-16-28(15-12-18-7-5-4-6-8-18)21(27)17-19-9-10-20(29)24(32-25)23(19)26/h4-10,21,29H,3,11-17H2,1-2H3/t21-,25+,26+,27-/m1/s1 ☒N
  • Key:YNNFSTLAUJEYHI-NVSKSXHLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

N-Phenethyl-14-ethoxymetopon is a drug that is a derivative of metopon. It is a potent analgesic, around 60 times stronger than morphine and produces significantly less constipation.[1]

N-Phenethyl-14-ethoxymetopon acts as an

δ-opioid receptors, with a Ki of 0.16 nM at μ and 3.14 nM at δ.[2]

See also

References

  1. PMID 16584118
    .
  2. PMID 15857143
    .


Stub icon

This analgesic-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=N-Phenethyl-14-ethoxymetopon&oldid=1204979942"