Isobutyrylfentanyl

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Isobutyrylfentanyl
Legal status
Legal status
Identifiers
  • 2-methyl-N-phenyl-N-[1-(1-phenylpropan-2-yl)piperidin-4-yl]propanamide
JSmol)
  • CC(C)C(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3
  • InChI=1S/C23H30N2O/c1-19(2)23(26)25(21-11-7-4-8-12-21)22-14-17-24(18-15-22)16-13-20-9-5-3-6-10-20/h3-12,19,22H,13-18H2,1-2H3
  • Key:WRPFPNIHTOSMKU-UHFFFAOYSA-N

Isobutyrylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold online as a designer drug.[1] It is believed to be around the same potency as butyrfentanyl[2] but has been less widely distributed on illicit markets, though it was one of the earliest of the "new wave" of fentanyl derivatives to appear, and was reported in Europe for the first time in December 2012.[3]

Side effects

Side effects of

respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.[4] A new wave of fentanyl analogues and associated deaths began in around 2014 in the US, and have continued to grow in prevalence; especially since 2016 these drugs have been responsible for hundreds of overdose deaths every week.[5]

Legal status

Isobutyrylfentanyl is a Schedule I controlled drug in the USA since 1 February 2018.[6]

See also

References

  1. PMID 28635020
    .
  2. S2CID 22092512
    .
  3. ^ Europol 2012 Annual Report on the implementation of Council Decision 2005/387/JHA
  4. PMID 25976511
    .
  5. S2CID 21404877
    .
  6. ^ "Schedules of Controlled Substances: Temporary Placement of Seven Fentanyl-Related Substances in Schedule I". Federal Register. 1 February 2018.
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