Pentamorphone

Source: Wikipedia, the free encyclopedia.
Pentamorphone
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 4,5α-Epoxy-3-hydroxy-14β-pentylamino-17-methyl-7,8-didehydromorphinan-6-one
JSmol)
  • CCCCCN[C@@]12C=CC(=O)[C@H]3[C@@]14CCN([C@@H]2CC5=C4C(=C(C=C5)O)O3)C
  • InChI=1S/C22H28N2O3/c1-3-4-5-11-23-22-9-8-16(26)20-21(22)10-12-24(2)17(22)13-14-6-7-15(25)19(27-20)18(14)21/h6-9,17,20,23,25H,3-5,10-13H2,1-2H3/t17-,20+,21+,22-/m1/s1
  • Key:NRPCWSUJMWEFOK-KDXIVRHGSA-N
  (verify)

Pentamorphone (14β-pentylaminomorphinone, RX-77989) is a semi-synthetic

respiratory depression compared to other potent opioid agonists,[3] but its analgesic effects were somewhat disappointing in human trials,[4] and while pentamorphone had some slight advantages over fentanyl[5]
these were not sufficient to warrant its introduction into clinical use.

References

  1. S2CID 35949040
    .
  2. S2CID 6715423
    .
  3. S2CID 30738025
    .
  4. S2CID 30636072
    .
  5. PMID 7522977
    .


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