CD72

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CD72 molecule
Identifiers
SymbolCD72
Chr. 9 p
Search for
StructuresSwiss-model
DomainsInterPro

CD72 (Cluster of Differentiation 72), also known in

T-cell interaction. It is a ligand for CD5.[1]

CD72 is a regulatory protein on B lymphocytes. The cytoplasmic tail of CD72 contains two potential immunoreceptor tyrosine-based inhibitory motifs, one of which has been shown to recruit the tyrosine phosphatase SHP- 1. These features suggest a negative regulatory role for CD72. CD72 is a nonredundant regulator of B-cell development and a negative regulator of B-cell responsiveness.[2]

See also

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External links

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